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Source publication
Objective
The aim of this study was to describe the use of dengue warning signs by pediatric healthcare staff in the Brazilian public health care system.
Methods
Cross-sectional study (2012) with physicians, nurses, and nurse technicians assisting children in five health care facilities. Participants reported the use and importance of dengue warni...
Citations
... Healthcare providers and researchers employed different criteria to define the warning signs, which led to diverse application of the guideline for the diagnosis and treatment of dengue patients. Therefore, there is an urgent need for the clear definitions of the warning signs and the severities in order to prevent unnecessary hospitalizations and to optimize triage and management [10][11][12][13]. Few studies have investigated the definitions used by healthcare providers on the field and their subsequent outcomes. ...
Background
To investigate the knowledge, attitudes, and practices of the healthcare professionals (HCPs) including physicians and nurses regarding dengue transmission, diagnosis and clinical classification using the warning signs of World Health Organization (WHO) 2009 classification.
Results
Out of 471 respondents from three countries, 80.9% of physicians and 74% of nurses did not receive previous training regarding the dengue infection. The majority of respondents could identify the primary dengue vector (86%), while only a third of HCPs knew the biting time of dengue mosquitoes. Only half of our respondents knew about immunity induced by serotypes; Moreover, half of our participants could determine the diagnostic tests. On the other hand, about 90% of the respondents took responsibility for talking to the patients about preventive measures. Our respondents also showed wide variations in definition of warning signs listed in the WHO 2009 classification. Multivariate analysis linked the impact of different cofactors including prior training on dengue infection, type of profession, frequency of taking care of dengue patients and country on how HCPs defined these warning signs.
Conclusions
This study could declare the variation in employing the warning signs listed in the WHO 2009 classification. We have figured that most of the HCPs did not take prior training on the dengue viral infection; Also, we found gaps in the knowledge regarding various topics in dengue fever. This paper recommends the gathering of efforts to establish the proper knowledge of dengue infection and the warning signs listed by the WHO.
... Dengue is an acute febrile disease caused by a flavivirus with four known serotypes (DENV-1, DENV-2, DENV-3, and DENV-4). The four serotypes can lead to variable clinical presentations, ranging from asymptomatic to severe forms [7]. ...
Introduction: The aim of the study was to determine the clinical and hematological profile in patients with Dengue fever. Materials and Methods: This was a prospective study done at Malla Reddy Medical College for Women, Telangana, for a period of six months. A total of 110 cases of dengue infection were studied. The patient demographics, clinical symptoms, hematological characteristics such as hemoglobin, total leucocyte count, platelet count, serological studies and abdominal ultrasound findings were noted. Results: In the present study, 85/110 (77.2%) cases were of dengue fever, 20/110 (18.1%) were dengue hemorrhagic fever (DHF) and 05/110 (4.5%) were of dengue shock syndrome (DSS). Patient age ranged from 0- 12 years. Majority, 55/110 (50%) were among 6-8 years. Males were affected more than females (59% boys and 41% were girls). Moderate thrombocytopenia was seen in 54.5 % of cases and raised hematocrit (>47%) was observed in 22.7 % cases. Most of the cases 75 (68.1%) were noted in September and October. Conclusion: Dengue is a common viral infection which may have serious consequences especially in children. Simple haematological parameters along with serological tests and ultrasound of abdomen are helpful in the diagnosis and appropriate management of these patients.
... The four serotypes can lead to variable clinical presentations, ranging from asymptomatic to severe forms. 5 Children represent more peculiar characteristics since dengue diagnosis, and recognition of severe forms are both more difficult to find than in adults. The common signs and symptoms are fever, headache, myalgia, arthralgia, and bleeding manifestations. ...
... The majority of studies showed that most frequently associated of signs and symptoms to children with SD were: spontaneous bleeding, hepatomegaly, and signs of plasma leakage, such as ascites and pleural effusion, abdominal pain, hemoconcentration and thrombocytopenia, and elevated plasma levels of the liver enzyme such serum glutamic pyruvate transaminase (SGPT), serum glutamic oxaloacetic transaminase (SGOT). 5,9,10 These findings on severe dengue infection should be given attention to prevent complications and deaths. Therefore, the aim of this study is to investigate clinical profile and to find the warning signs of dengue infection in children also their association with severe dengue. ...
Dengue fever is one of the most important emerging vector-borne viral diseases. Approximately 500,000 out of 100 million cases develop to severe dengue infection. Patient with severe dengue (SD) can be predicted by clinical profile, laboratory and warning sign which could be saved by early interventions.This was a retrospective descriptive-analytic study to investigate clinical manifestations, laboratory and warning signs ofchildren with dengue infection in Haji Adam Malik hospital during January 2014–May 2016. Through medical records, we had selected 140 cases which fulfilled research criteria.Cases were classified as SD (n=28) and NSD (n=112). Most common clinical manifestations for NSD were abdominal pain (39.3%), myalgia (39.3%), headache (37.1%), mucosal bleeding (36.4%) while for SD were shock (15.7%), mucosal bleeding (15.7%), clinical fluid accumulation (15%), shortness of breath (14.3%). SGPT >1000IU/L (5 cases), SGOT >1000IU/L (9 cases), PT (10 cases) and aPTT (16 cases) were abnormal in SD. Severe dengue was frequently found in the range of white cell count 1000-4000/L and platelet count 20,000-50,000mm/uL. Clinical manifestations, warning sign, and laboratoryfinding, were different between SD and NSD.
... To make the pneumonic easier to memorize, the chosen points appear in alphabetical order. This approach was applied according to previously reported experiences with establishing warning signs for primary immunodeficiencies [13,14] and other diseases [15,16] . Symptoms, signs, diagnosis, and responses to therapy were condensed as warning signs listed in alphabetical order ( Fig. 1 ). ...
Hereditary angioedema (HAE) with C1 inhibitor deficiency is a genetic disorder that clinically manifests with attacks of angioedema in the subcutaneous and submucosal tissues, mainly in the extremities, abdomen, and upper airway. During attacks, vascular permeability is increased due to increased bradykinin (BK). This means that special therapies are needed for attacks that do not respond to traditional antiallergic therapies involving antihistamines, corticosteroids, and epinephrine. The recurring attacks may disable patients and lead to frequent visits to emergency rooms where misdiagnoses are common. HAE attacks may be fatal when upper-airway edema occurs, if proper treatment with a C1 inhibitor concentrate or BK receptor antagonist is not administered or an emergency tracheostomy is not performed. We propose a mnemonic method for the warning signs of HAE for the use as a diagnostic tool, i.e., the so-called "ABC" of the warning signs of HAE. The letters represent the following: A = Angioedema, B = Bradykinin, C = C1 inhibitor, D = Distress factors, E = Epinephrine nonresponsive, F = Family history, and G = Glottis/Gastrointestinal edema. To avoid fatalities, medical staff and patients, including family members, must be aware of HAE. An alphabetical mnemonic method has been developed and we hope it may benefit patients.
