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Nanotechnology has been commonly used in a variety of applications in recent years. Nanomedicine has also gotten a lot of attention in the medical and treatment fields. Ultrasonic technology is already being used in research as a powerful tool for manufacturing nonmaterial and in the decoration of catalyst supports for energy applications and mater...
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... It is a key technique for synthesizing and processing nanoscale materials, especially in nanotechnology. Ultrasonic is frequently used in joint ventures with the nanotechnology from the past few years and bring tremendous success in various diseases diagnosing and treatment (Liu & Ge, 2022). Leaf extracts from Nasturtium officinale L. and Vaccinium arctostaphylos L. were used to synthesize biogenic ZnO nanoparticles using ultrasound techniques that had several biomedical applications ). ...
Industrial wastewater alludes to an amalgamation of an array of toxic pollutants that pose significant risks to human health and the environment. Traditional wastewater treatment methods often struggle to effectively remove these pollutants. However, recent advancements in nanotechnology combat this bottleneck of eliminating the pollutants by engendering nanoparticles as potential detoxifiers for industrial wastewater. This review aims to explore the applications of nanoparticles in wastewater treatment, focusing on their ability to effectively remove and detoxify toxic contaminants that act as pollutants. It is an elaborate and comprehensive description of various types of nanoparticles, their synthesis methods, mechanisms of pollutant removal, and their overall effectiveness in detoxifying industrial wastewater. This state of art information shall aid in further research and biotechnological applications of nanoparticles for wastewater management.
... An alternative technique that is suitable for laboratory-scale fabrication and requires less labor is the presentation of ultrasonic energy in a mixture of cell membranes and NP cores; in this way, diverse types of NPs are created with desired capabilities and directed at various targets [147]. ...
Nanomedicines have made remarkable advances in recent years, addressing the limitations of traditional therapy and treatment methods. Due to their improved drug solubility, stability, precise delivery, and ability to target specific sites, nanoparticle-based drug delivery systems have emerged as highly promising solutions. The successful interaction of nanoparticles with biological systems, on the other hand, is dependent on their intentional surface engineering. As a result, bio-mimetic nanoparticles have been developed as novel drug carriers. In-depth knowledge of various biomimetic nanoparticles, their applications, and the methods used for their formulation, with emphasis on the microfluidic production technique, is provided in this review. Microfluidics has emerged as one of the most promising approaches for precise control, high reproducibility, scalability, waste reduction, and faster production times in the preparation of biomimetic nanoparticles. Significant advancements in personalized medicine can be achieved by harnessing the benefits of biomimetic nanoparticles and leveraging microfluidic technology, offering enhanced functionality and biocompatibility.
... Nowadays, nanomedicine and nanotheranostic advances are hugely growing for therapeutic and diagnostic purposes [13]. Nanotheranostics, which are usually generated through complex synthetic protocols, are nanoparticles designed to provide real-time information about targeted treatment in vitro/vivo [14,15]. As such, nanotheranostics' biomedical application relies on passive particle accumulation in the diseased cells/tissues via enhanced permeability and retention effect (EPR); this is usually achieved with biological coating (i.e., albumin, peptides) or polyethylene glycol (PEG) surface modification. ...
Nanoparticles have garnered considerable scientific attention in recent years due to their diagnostic and therapeutic applications in cancer. The purpose of this study was to determine the effect of superparamagnetic iron oxide nanoparticles (Fe3O4 MNPs) on the induction of apoptosis in human colorectal adenocarcinoma cell line (HT-29) cells. The purpose of this study was to elucidate the mechanisms of apoptosis induced by Fe3O4 MNPs following MTT assay and to determine the optimal dose of 2.5 g/mL for inducing apoptosis in HT-29 cells. In HT-29 cells, Fe3O4 MNPs increased reactive oxygen species (ROS), calcium ion (Ca²⁺), and DNA damage. Additionally, the Fe3O4 MNPs significantly increased caspase 3 and 9 expression and decreased Bcl-2 expression at the protein and mRNA levels when compared to the control group (P = 0.0001). Fe3O4 MNPs also induced apoptosis in cancer cells by increasing the level of (ROS) and intracellular Ca²⁺, followed by an increase in caspase 3 and 9 expression and a decrease in Bcl-2 expression and direct DNA damage. Fe3O4 MNPs are an appropriate choice for colon cancer treatment based on their cell toxicity and induction of apoptosis in HT29 cells.
In present study, the effects of orange peel essential oil and ultrasonic treatment on properties of corn starch based edible coating and films including their effects on the shelf life of citrus (Kinnow) fruits are investigated. The ultrasonic approach and essential oil significantly improves the quality characteristics of edible coating formulations, stability, and rheological behaviour of coating materials by reducing the particle size, including antimicrobial activity. The particle size of the coating materials reduces from 2495 nm (control) to 298.8 nm by ultrasonication treatment with improved stability (−39.251 mV) as well as antimicrobial activity. The tensile strength (720 N) and solubility (32.40%) of the CSEOU edible film are also improved as compared to CSEO and CS edible films. The coating formulation enriched with essential oil and ultrasonic treatment (CSEOU) improves the shelf‐life of Kinnow by retarding weight loss (PLW) and microbial load, as well as maintaining higher acidity (TA), total soluble solids (TSS), and higher antioxidant activity. CSEOU treated samples indicate lowest weight loss (24.57%), pH (3.89) with higher TA (3.999%), firmness (494.229 N), phenolic (26.17 mg 100 g ⁻¹ ), flavonoid (34.11 mg 100 g ⁻¹ ), antioxidant (49.04%), and antimicrobial activity against A. niger , E. coli and S. aureus as compared to other samples.
