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Colon carcinoma is one of the most common malignant tumours and the second cause of cancer-related deaths in developed countries. The objective of the research was to investigate the p53 expression in colorectal cancer and compare the expression levels of p53 with the macroscopic appearance and manner of growth of the tumours, followed by detection...
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With the advances in high throughput technologies, increasing amounts of cancer somatic mutation data are being generated and made available. Only a small number of (driver) mutations occur in driver genes and are responsible for carcinogenesis, while the majority of (passenger) mutations do not influence tumour biology. In this study, SomInaClust...