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Tumor showing composite differentiation to schwannoma and hemangioma (H&E 20x).

Tumor showing composite differentiation to schwannoma and hemangioma (H&E 20x).

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The most common peripheral nerve sheath and vascular tumors are schwannomas and hemangiomas, respectively. These tumors can affect any organ system and usually occur as separate morphologic and diagnostic entities. Herein, we describe the case of a 24-year-old woman with a tumor demonstrating composite differentiation to both cavernous hemangioma a...

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... Cavernous haemangiomas are less prevalent than the capillary type and are composed of large dilated vascular channels, with ill-dened 6,7 edges involving deep structures like viscera, bone and muscles . Lesions larger than 5 cm are more likely to be symptomatic and 5 vulnerable to consequences, including bleeding and rupture . Vascular malformations have traditionally been considered to be 8 developmental anomalies. ...
Article
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Cavernous haemangiomas are vascular tumours that can occur in any organ system. Schwannomas are common benign peripheral nerve sheath tumours arising from differentiated Schwann cells. However, the concurrence of peripheral nerve sheath tumours and cavernous haemangiomas is rare. So far, only 40 cases have been reported in the literature. Most tumours documented to coexist with cavernous haemangiomas are Schwannomas and Neurobromas. Herein, we discuss a case of a 48-year-old male patient who presented with a slow growing lesion in the right ankle region revealing composite differentiation of both cavernous haemangioma and ancient schwannoma. The aim of this case report is to make clinicians, pathologists and radiologists aware of such uncommon tumours to avoid potential pitfalls during diagnosis and treatment.