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Total number of recommended items in four major food groups listed in the FFQ for each ‘Blood-Type’ diet (A). Diet score distribution for each ‘Blood-Type’ diet (B). doi:10.1371/journal.pone.0084749.g001 

Total number of recommended items in four major food groups listed in the FFQ for each ‘Blood-Type’ diet (A). Diet score distribution for each ‘Blood-Type’ diet (B). doi:10.1371/journal.pone.0084749.g001 

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The 'Blood-Type' diet advises individuals to eat according to their ABO blood group to improve their health and decrease risk of chronic diseases such as cardiovascular disease. However, the association between blood type-based dietary patterns and health outcomes has not been examined. The objective of this study was to determine the association b...

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... According to the AJCC staging system, ATC patient was in the fourth stage IVB with pT4a N1 M0, both HCC and FTC patients were at first stage with pT3a NX MX and pT1b N0 respectively, while MTC was in third stage with pT3a N1a Mx. Among PTC group only 2.2% of PTCs were in stage II with pT3a N1a, and the remaining were in the first stage with different pathological staging as described in table (4)(5). Email: utjmed@utq.edu.iq ...
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Background: The ABO and Rh system have a great association to different kind of malignancy as mentioned in the literature. The data about prevalence of blood group with thyroid malignancies were limited in the literature; we aimed to record the relationship of different ABO and Rh blood groups with different malignant thyroid tumors. Methodology: the demographics, ABO blood group, Rh factor, histopathological type of malignant thyroid tumors were recorded for each patient with malignant thyroid tumor (MTT); then we evaluated the association between different blood group types with different histopathological pattern. Results: the commonest type of malignant thyroid carcinoma was Papillary thyroid carcinoma (PTC) [n=46, (92%)], while all other types were uncommon, they were follicular thyroid carcinoma [(n=1) 2%], medullary thyroid carcinoma [(n=1) 2%], Hürthle cell carcinoma [(n=1) 2%] and anaplastic thyroid carcinoma [(n=1) 2%]., the blood group A with Rh positive was the most frequent [n= 17, (34%)], , the O+ve was [n=15 (30%)], B+ve [n=10 (20%)], while AB-ve [n=3 (6%)] while a small number was Rhesus negative. The A+ve blood group was the commonest blood group in PTC patients (34.8%), followed by O+ve (30.4%). Conclusion: Blood group A+ve is the most frequently reported among cases of papillary thyroid carcinoma, which is the most common MTT.
... Studies made on this hypothesis were inconclusive, but one study on ABO genotype and cardio-metabolic risk factor revealed that adherence to blood type diet had favorable effects on some cardio-metabolic risk factors as lowering BMI, waist circumference, blood pressure, serum cholesterol, triglycerides, and insulin with variations between blood types. However, it was also found that there is no significant association between these changes and blood type and these results does not support the "blood-type" diet hypothesis [21]. ...
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The relationship between nutrition and genes has long been hinted at and sometimes plainly associated with certain diseases. Now, after many years of research and coincidental findings, it is believed that this relationship, termed “Nutrigenomics,” is certainly a factor of major importance in various conditions. In this review article, we discuss nutrigenomics, starting with basics definitions and enzymatic functions and ending with its palpable association with cancer. Now, diet is basically what we eat on a daily basis. Everything that enters through our alimentary tract ends up broken down to minute molecules and amino acids. These molecules interact with our microbiome and genome in discreet ways. For instance, we demonstrate how proper intake of probiotics enhances beneficial bacteria and may alleviate IBS and prevent colorectal cancer on the long term. We also show how a diet rich in folic acid is essential for methylenetetrahydrofolate reductase (MTHFR) function, which lowers risk of colorectal cancer. Also, we discuss how certain diets were associated with development of certain cancers. For example, red and processed meat are highly associated with colorectal and prostate cancer, salty diets with stomach cancer, and obesity with breast cancer. The modification of these diets significantly lowered the risk and improved prognosis of these cancers among many others. We also examined how micronutrients had a role in cancer prevention, as vitamin A and C exert anti-carcinogenic effects through their function as antioxidants. In addition, we show how folic acid prevent DNA mutations by enhancing protein methylation processes. Finally, after a systematic review of myriad articles on the etiology and prevention of cancer, we think that diet should be a crucial feature in cancer prevention and treatment programs. In the future, healthy diets and micronutrients may even be able to successively alter the liability to genetic mutations that result in cancer. It also will play a role in boosting treatment and improving prognosis of diagnosed cancers. Keywords Nutrigenomics, Nutrigenetics, Microbiome, MTHFR, Cancer, Personalized Nutrition, Viral infection
... В одном из исследований изучался индекс массы тела, артериальное давление, уровень холестерина и инсулина в сыворотке крови у молодых людей и оценивался их рацион в течение месяца в контексте диеты по группе крови. Хотя между этими группами были выявлены значительные различия в исследованных показателях, не было обнаружено значительной связи между диетой и этими показателями (Wang, 2014). Еще одно исследование продемонстрировало, что у людей, придерживающихся веганской диеты с низким содержанием жиров, не было обнаружило связи между группой крови и уровнем липидов или другими метаболическими показателями (Barnard, 2021). ...
... Some research suggests that certain blood types may be associated with an increased risk for certain diseases. However, it is essential to note that blood type alone is not a significant risk factor for most conditions, and other factors such as lifestyle, diet, and genetics play a much more substantial role (5). Blood type A may have a slightly increased risk of developing certain digestive tract cancers, such as stomach cancer (6). ...
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Aim: Many factors affect the diagnostic value of the fine-needle aspiration biopsy applied for these thyroid nodules. I aimed to investigate whether one of these factors would be ABO blood groups and Rh factor and examine the relationship of these factors with the Bethesda categorization. Additionally, I aimed to evaluate ABO blood groups and Rh factors in patients with thyroid cancer. Material and Method: This study was planned in a cross-sectional retrospective design. The data of the patients were obtained from the hospital data bank. In the analysis of 801 patients following the acceptance criteria, 412 patient data were obtained. Patients were divided into 4 (O, A, B, and AB groups) according to their blood groups and analyzed for nodules (solitary/ multinodular). Nodules were divided into malignant and benign, according to histopathological diagnosis, and all were analyzed. Results: There was no difference in analyzing the demographic data according to the blood groups. The rates of the FNAB history were 51 (32.3%), 39 (24.2%), 14 (26.4%), and 13 (32.5%) in the same order of blood groups (p=0.393). In the analysis of the nodule type, multinodular did not differ from solitary nodules among the blood groups [O: 141 (89.2%); A:140(87%), B: 46(86.8%), and AB: 35(87.5%)]. Thyroid function status (euthyroid, hypothyroid, or hyperthyroid) was similar for all the blood groups (p=0.815). The O-group had 1 (0.6%) patient with Bethesda score-6, and the A-group had 2 (1.2%) patients with Bethesda score-6. For Bethesda score-5, per blood group had 2 patients. The histopathological distribution of malign nodules (p=0.782) is as follows: O-groups: 6 (33.3%) (Rh+:27%; Rh-:5,5%), A groups: 7(63,6%) (Rh+:54,5%; Rh-:0,9%), B groups: 2(20%)(Rh+:20%; Rh-:0%) and AB groups: 1(33%) (Rh+:33%) Rh-:0%). Conclusion: Malign nodule rate was highest in the A-group and lowest in the B groups, although it did not differ in the overall analysis. No relationship was found between the Bethesda categorization of nodules, their sizes, type of nodules, type of thyroid cancer, and ABO blood groups.
... In addition, those in the AB blood group should be fed with proteins of both vegetable, fruit and animal origin. There are many people all over the world who adopt and practice this diet (Wang et al. 2014). ...
... At the same time, the "Blood-Type" diet concept is not supported by other research, which indicates that following specific "Blood-Type" diets has positive effects on several cardiometabolic risk factors. However, these relationships were not dependent on an individual's ABO genotype [13]. To the best of our knowledge, there is no previous study that explored the association between blood group and the response to bariatric surgery. ...
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Objectives: To explore the relationship between the blood group of patients and their response to bariatric surgery and to identify predictors of better outcomes. Methods: This was a retrospective cross-sectional analysis of patients who underwent laparoscopic sleeve gastrectomy for morbid obesity between 2014 and 2020 at King Saud University Medical City in Riyadh, Saudi Arabia. Results: This study included 1434 individuals. The mean change in BMI (pre- versus post-BMI) differed statistically significantly between blood groups (p ≤ 0.01). The greatest drop in body weight was seen in individuals with the AB-negative blood type (56.0 (21.4) kg), which corresponds to the greatest percentage of reduction from baseline (47.7% (14.8)). The mean BMI of the patients decreased by 34.7% (9.2) from a mean pre-operation BMI of 45.5 (8.4) kg/m2 to 29.7 (6.1) kg/m2 (p ≤ 0.001). After laparoscopic sleeve gastrectomy, male patients and those with the B-negative blood type are more likely to see a greater BMI reduction (pre-operation compared to post-operation) (p ≤ 0.05). Conclusions: For morbidly obese patients, laparoscopic sleeve gastrectomy demonstrated promising weight loss outcomes. Blood groups may be able to predict the success rate of bariatric surgery in morbidly obese patients.
... In addition, those in the AB blood group should be fed with proteins of both vegetable, fruit and animal origin. There are many people all over the world who adopt and practice this diet (Wang et al. 2014). ...
... Wang et al. demonstrated that, although adhering to some blood-type diets may reduce cardiometabolic risk factors, these links are independent of an individual's ABO group [5]. On the other hand, research on the ABO group system proposed an association between ABO blood groups and a variety of diseases such as hepatitis [6], thrombotic disorders [7], metabolic and cardiovascular diseases [8,9], cognitive disorders and circulatory diseases. ...
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The ‘Blood-Type’ diet advises individuals to eat according to their ABO blood group to improve their health and decrease the risk of chronic diseases. However, the food preferences of individuals with different blood groups have not been examined. The aim of our study was to investigate, in healthy regular blood donors (rBDs), the associations of smoke, alcohol, caffeine, vitamin and fat intake with their different blood groups and if ABO groups could be a potential predictor tool for disease prevention. A total of 329 volunteers were divided into four groups according to their ABO types: Group 1 (A) comprised 141 rBDs; Group 2 (B), 65 rBDs; Group 3 (O), 96 rBDs; and Group 4, 27 rBDs. Additionally, they were divided into two groups according to their rhesus types and their preferences for smoke, too. Dietary intake was assessed using 3-day food recall and the Food Processor computer program for nutrient analysis. Alcohol, caffeine, sugar and Vitamin D consumption were significantly (p < 0.05) higher in the O group. The A group presented statistically significantly (p < 0.05) greater preferences for cholesterol intake and a higher trend for smoking (25%) habits compared with all the other groups, whereas Group B preferred more fatty foods. The blood group AB appeared to be the most controlled food intake group. Regarding the rhesus comparisons, alcohol; caffeine; and Vitamin C, D, E and K consumptions were significantly (p < 0.05) higher in rhesus-positive individuals than their rhesus-negative counterparts. For the non-smoker group, compared with the smokers, a higher consumption of Vitamin D and fibers was found. In conclusion, in the present study, statistically significant correlations of the ABO and rhesus system with some dietary parameters were found, indicating a consequent influence of these preferences on the progression of different diseases.
... So, they may experience many health problems. The lectin-connection has been extensively studied in Coeliac disease though the results were mixed and inconclusive [14,15]. A few studies have already examined the association between blood groups and intestinal disorders, but the results were controversial. ...
... ABO blood type studies stay an actual topic of research. They have shown that ABO blood types are associated with cardiovascular disease, cancer, severe malaria (Plasmodium falciparum), but also with depression and anxiety (LIUMBRUNO et al., 2013;HANSEN et al., 2005;YAMAMOTO et al., 2012;FRY et al., 2008;RICH et al., 2013;et al., 2014). During the COVID19 pandemic, susceptibility to SARS CoV-2 dependent on ABO blood type has been demonstrated as well (DAI, 2020;ZHAO et al., 2020). ...
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Tobacco smoking is major risk factor for development of chronic obstructive pulmonary disease (COPD), which appears in 15-20% of smokers. Apart from smoking, exposure to polluted air and various noxae, and several genetic factors influence its development as well. The ABO blood type distribution varies among populations in the world, but also within subpopulations. A large number of studies have shown a correlation between blood types and the pathology of various diseases. These markers, used in population genetic research, have mainly shown deviations in the representation of blood groups in different diseases, compared to the general population. The aim of this study was to determine the ABO blood types distribution in patients with COPD compared to the general population, and their possible association with COPD stage, patients’ nutritional status and lung function impairment. This observational, prospective study included 150 patients (68.7% men and 31.3% women), average age 64.80 ± 8.38 years, diagnosed with COPD. Data were collected at the Clinical Center of Montenegro in Podgorica and at the Special Hospital for Lung Diseases Brezovik in Niksic. Determination of blood types of the ABO system and Rh factors for all subjects was performed at the Blood Transfusion Center in Podgorica. Apart from patients’ tobacco smoking status (duration of smoking and the number of cigarettes smoked per day expressed in pack/years for current smokers and former smokers), we also analyzed their exposure to various other noxae, their body mass index, and lung function in correlation to ABO blood type and Rh factor, and performed statistical analysis. We found a significant difference in the distribution of ABO blood types in patients with COPD compared to the general population. The highest frequency of blood type A was found in patients with COPD. We also found the lowest average values of spirometry parameters in that group, which represented majority of those patients with respiratory insufficiency having the most severe stage of the disease. Combined blood types A, B and were significantly more common in patients with COPD in comparison to blood type O, which is the least represented (23.3%). The least obstructive disturbance of pulmonary ventilation was found in the patients with B type. Respiratory insufficiency showed differences in gender representation, found in 40.4% of women, and in 25.2% of men with terminal phase of COPD. The prevalence of AB, higher than expected, decreases with the severity of the disease.