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Three-dimensional neonatal view—various cleft deformities. 

Three-dimensional neonatal view—various cleft deformities. 

Context in source publication

Context 1
... examination may detect clefts of the lip and alveolus unlike cleft palate, which is difficult to diagnose through routine screening ( Figure 5). Additional examinations and tests can confirm the presence of deformity. These include cephalic presentation of the child, low body mass index of the mother, and examination preferably around the 20th gestational week [24]. Moreover, information about family history should be addressed so that provisions for postnatal measures in adequately equipped hospitals can be made in with improvement in ultrasound ...

Citations

... The course of treatment for cleft lip and/or cleft palate patients consists of several stages, with surgery being the first corrective procedure to go through. 5,6 It is important to conduct surgery as early as possible as it is crucial to make the patient has a (close to) normal anatomical structure that can function as (near to) normal as possible. 7 Unfortunately, similar to any other invasive approach, surgery has postoperative consequences, one of which is postoperative pain, regardless of the existing postoperative pain management. ...
Article
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Objective Acute pain is one of the most common pains experienced by post-cleft lip or cleft surgery patients regardless of the administration of analgesic agents. This current study aimed to evaluate the efficacy of a curcumin patch as an adjuvant analgesic agent on the post-cleft lip and cleft palate surgery patients. Materials and Methods Fifty-five (33 male; 22 female) participants aged 36 months or less are recruited in this pragmatic trial and randomly assigned to a control group, where no curcumin patch was applied; or the experimental group, where the participants wore a curcumin patch with a dosage of 100mg. All participants (regardless of the group) received a standardized postsurgery analgesic agent immediately after the surgery was completed. A face, leg, activity, cry, and consolability (FLACC) scale was used to evaluate pain levels for three subsequent time points. Statistical Analysis All data were then analyzed by using the Mann–Whitney U test to compare the mean differences between the two groups. Results The results of the current study revealed that there was no significant difference found between the control and the experimental group when mean pain scores were compared for the first evaluation time. Yet, there was a significant difference ( p <0.01) between the two groups' mean pain scores on the second evaluation time. Conclusion Curcumin patch was found to be effective when used as an adjuvant analgesic agent to reduce acute-orofacial postsurgery pain in cleft lip and cleft surgery patients.
... A disruption of the relationship leads to incomplete fusion and the development of a cleft of the face, lips and/or palate. 26,27 A cleft lip and/or palate (CL/P) is the most common example of a facial cleft and a leading congenital craniofacial deformity. 27 The parents of infants with a CL/P are usually made aware of the condition before birth, through routine ultrasound checks during pregnancy. ...
... 26,27 A cleft lip and/or palate (CL/P) is the most common example of a facial cleft and a leading congenital craniofacial deformity. 27 The parents of infants with a CL/P are usually made aware of the condition before birth, through routine ultrasound checks during pregnancy. 27,28 The present case report demonstrates that presurgical maxillary orthopaedic treatment performed in accordance with NAM procedures, together with a longterm review, produces positive treatment results. ...
... 27 The parents of infants with a CL/P are usually made aware of the condition before birth, through routine ultrasound checks during pregnancy. 27,28 The present case report demonstrates that presurgical maxillary orthopaedic treatment performed in accordance with NAM procedures, together with a longterm review, produces positive treatment results. 29,30 Although the encouraging effects of NAM in patients affected by a unilateral cleft lip and palate (UCLP) have been described by Padovano et al., 30 the long-term effects of the procedure are unclear. ...
Article
Cleft lip and palate (CLP) are conditions that require long-term management and review from infancy to adolescence. Surgical procedures become easier when nasoalveolar moulding (NAM) measures are applied during the neonatal period. Orthodontic treatment provided for these patients during the progressive dentition developmental periods can achieve positive aesthetic and functional results. In patients affected by a CLP, the lateral incisor in the cleft region is usually missing and multidisciplinary prosthodontic rehabilitation of the edentulous space is often required. In the present case report, positive results of NAM, coupled with orthodontic and prosthodontic treatment are presented for a CLP patient who began management during the neonatal period. In addition, a minimally invasive aesthetic restoration is presented as a solution for the prosthodontic rehabilitation of a missing lateral incisor.
... A disruption of the relationship leads to incomplete fusion and the development of a cleft of the face, lips and/or palate. 26,27 A cleft lip and/or palate (CL/P) is the most common example of a facial cleft and a leading congenital craniofacial deformity. 27 The parents of infants with a CL/P are usually made aware of the condition before birth, through routine ultrasound checks during pregnancy. ...
... 26,27 A cleft lip and/or palate (CL/P) is the most common example of a facial cleft and a leading congenital craniofacial deformity. 27 The parents of infants with a CL/P are usually made aware of the condition before birth, through routine ultrasound checks during pregnancy. 27,28 The present case report demonstrates that presurgical maxillary orthopaedic treatment performed in accordance with NAM procedures, together with a longterm review, produces positive treatment results. ...
... 27 The parents of infants with a CL/P are usually made aware of the condition before birth, through routine ultrasound checks during pregnancy. 27,28 The present case report demonstrates that presurgical maxillary orthopaedic treatment performed in accordance with NAM procedures, together with a longterm review, produces positive treatment results. 29,30 Although the encouraging effects of NAM in patients affected by a unilateral cleft lip and palate (UCLP) have been described by Padovano et al., 30 the long-term effects of the procedure are unclear. ...
Article
Full-text available
Cleft lip and palate (CLP) are conditions that require long-term management and review from infancy to adolescence. Surgical procedures become easier when nasoalveolar moulding (NAM) measures are applied during the neonatal period. Orthodontic treatment provided for these patients during the progressive dentition developmental periods can achieve positive aesthetic and functional results. In patients affected by a CLP, the lateral incisor in the cleft region is usually missing and multidisciplinary prosthodontic rehabilitation of the edentulous space is often required. In the present case report, positive results of NAM, coupled with orthodontic and prosthodontic treatment are presented for a CLP patient who began management during the neonatal period. In addition, a minimally invasive aesthetic restoration is presented as a solution for the prosthodontic rehabilitation of a missing lateral incisor.
... A second study in 2007 described CL/P in one region of Oman (Al Dhahirah between 2003 and and showed the prevalence rate to be 1.4 per 1000 births (Patel, 2007). Cleft lip and/or palate conditions are complex and best addressed by a multidisciplinary team (Nahai et al., 2005;Zreaqat et al., 2017). The ultimate goal of the medical and psychosocial interventions is to restore function and aesthetic of the mouth, support normal development of speech and hearing, ensure good oral hygiene, and improve quality of life (Zreaqat et al., 2017). ...
... Cleft lip and/or palate conditions are complex and best addressed by a multidisciplinary team (Nahai et al., 2005;Zreaqat et al., 2017). The ultimate goal of the medical and psychosocial interventions is to restore function and aesthetic of the mouth, support normal development of speech and hearing, ensure good oral hygiene, and improve quality of life (Zreaqat et al., 2017). Surgery has to be done in a timely manner to avoid issues with feeding and speech development. ...
Article
Full-text available
Introduction Cleft lip and/or palate (CL/P) is the most common craniofacial anomaly. In Oman, the incidence of CL/P is estimated to be 1.5 per 1000 live births per year. Knowledge, awareness, and attitude toward CL/P help to optimize the management of the condition and reduce social and emotional stress among this group of children and their family. In this survey, we assessed the public awareness, knowledge, and attitude toward this deformity in the Sultanate of Oman. Method A cross-sectional study was conducted using validated questionnaire that was distributed using Google forms. Result A total of 739 participants completed the survey. The majority is aware of cleft lip (86.7%) and palate (63.2%). In general, attitude toward patients with CL/P was positive. Females had higher knowledge compared to males, 54.4% and 32.9%, respectively. Online resources were the main source of information. Conclusion There are variations in knowledge, awareness, and attitude toward CL/P among participants. Omani population needs to be educated more about CL/P, its complications if not treated, and the available treatment.
... [ Table 1]. [5,[15][16][17] ...
Article
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Clefts of the lip and palate are the congenital anomalies which may range from a small furrow in the lip to a complete separation of the two maxillary processes. They possess a significant social and financial burden to the individuals and their families. Numerous theories about the etiopathogenesis have been put forward from the past and numerous authors have classified them in different forms for easy understanding. Here in this review we have tried to compile the information from the past literature to present a brief update on various aspects of this entity.
... Individuals with clefts of the lip, palate, or alveolus often require interdisciplinary treatment into adulthood and thus they require timely and effective care. In addition, the repercussions of this disease affect the family nucleus and the social environment that in many cases may carry the financial burden of extensive treatment, and a variety of psychosocial challenges [13,15]. The economic impact of CL/P therapies on national health systems is difficult to estimate due to the number of analyses and examinations that every child born with a CL/P must go through for several years. ...
... interdisciplinary treatment into adulthood and thus they require timely and effective care. In addition, the repercussions of this disease affect the family nucleus and the social environment that in many cases may carry the financial burden of extensive treatment, and a variety of psychosocial challenges [13,15]. The economic impact of CL/P therapies on national health systems is difficult to estimate due to the number of analyses and examinations that every child born with a CL/P must go through for several years. ...
Article
Full-text available
Craniofacial bone defect anomalies affect both soft and hard tissues and can be caused by trauma, bone recessions from tumors and cysts, or even from congenital disorders. On this note, cleft/lip palate is the most prevalent congenital craniofacial defect caused by disturbed embryonic development of soft and hard tissues around the oral cavity and face area, resulting in most cases, of severe limitations with chewing, swallowing, and talking as well as problems of insufficient space for teeth, proper breathing, and self-esteem problems as a consequence of facial appearance. Spectacular advances in regenerative medicine have arrived, giving new hope to patients that can benefit from new tissue engineering therapies based on the supportive action of 3D biomaterials together with the synergic action of osteo-inductive molecules and recruited stem cells that can be driven to the process of bone regeneration. However, few studies have focused on the application of tissue engineering to the regeneration of the cleft/lip and only a few have reported significant advances to offer real clinical solutions. This review provides an updated and deep analysis of the studies that have reported on the use of advanced biomaterials and cell therapies for the regeneration of cleft lip and palate regeneration.
Article
Full-text available
Background: This study reviews the surgical and functional outcomes of children diagnosed with a bilateral cleft lip and palate and treated by the same surgical team following specific surgical protocols 18 years after surgery and during the follow-up. Methods: Based on a single-center retrospective design, demographic and surgical data were gathered by the authors from international institutions. Most of the data were quantitative in nature, and descriptive statistical and non-parametric tests were employed for analysis. All children born with a bilateral cleft from 1982 to 2002 were considered. Children affected by a syndrome were excluded. Complications and speech results were the main items measured. Results: Thirty patients were selected; 73.3% were treated using the inverse Malek procedure, and 26.7% underwent a modified two-stage procedure. Seventy percent developed an oronasal fistula. An alveolar bone graft was performed in 83%, and 53.3% underwent Le Fort osteotomy. Thirty-six percent required a pharyngeal flap, with good speech results. The median number of times general anesthesia was used among all the interventions considered was 5.5 (4.25–6). Conclusions: This study presents the long-term results of using the inverse Malek procedure to treat children with a bilateral cleft lip and palate. It is shown that this is related to a high risk of developing a fistula, but has good long-term speech results.
Chapter
A multidisciplinary craniofacial care approach is needed in the management and treatment of cleft lip and palate. Careful planning, constant communication and consultation with the different specialties on board create a better treatment plan. The dental specialists involved in the team can be very much beneficial to develop practical treatment options in the formulation of treatment objectives of the cleft patient. One of the common postsurgical outcomes encountered in the treatment of cleft palate is a palatal fistula. The choice for a cleft prosthesis to benefit both pediatric and adult patients are presented alongside the rationale of the given cleft device. The different types of cleft appliances used by the patient from feeding plates to obturators with speech devices greatly enhance the well-being, nourishment, and psychosocial behavior of the patient. Another adverse sequela of a postsurgical cleft palate closure is velopharyngeal insufficiency. It is a condition where the failure of the soft palate to come in contact with the posterior pharyngeal walls to create a velopharyngeal closure lead to defective speech. The palatopharyngeal bulb or a speech aid will mechanically compensate to create a velopharyngeal seal thus producing a coherent voice. The fabrication and construction of cleft devices are also presented in this chapter. The options provided in this chapter are all nonsurgical management of a palatal fistula from a dental perspective.