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Background and aim:
Fractional CO2 laser is therapeutic for acne atrophic scar, but its effect usually is limited after multiple sessions, with occasional adverse reactions. This study aimed to evaluate the efficacy and safety of a new modality combining ultra-pulse CO2 laser and fractional CO2 laser (multiple mode procedures [MMP]) in the treatme...
Context in source publication
Context 1
... average scores for improvements in color, unevenness and texture were 2.0 ± 0.9, 2.2 ± 0.9, 2.3 ± 0.8, respectively, with the highest in texture. Comparing the improvement scores of three different types of scars, MMP exerted the strongest effect on boxcar scars (GAS, 2.7 ± 0.8; color, 2.4 ± 0.9; distortion, 2.5 ± 0.9; texture, 2.6 ± 0.8), followed by icepick scars (GAS, 1.67 ± 0.8; color, 1.5 ± 0.7; deformation, 1.8 ± 0.8; texture, 1.87 ± 0.8) and rolling scars (GAS, 2.3 ± 0.8; color, 1.8 ± 0.6; deformation, 2.1 ± 0.8; texture, 2.3 ± 0.7) (Table 3). All patients tolerated the procedures well and showed varying degrees of burning, pain, edema and erythema, all significantly relieved after cold compress. ...Similar publications
Various treatment modalities have been applied to atrophic scars. Fractional CO2 laser treatment has attracted increasingly more attention because of its quicker recovery time and fewer side effects. However, its limitation of sculpting the edge is an urgent shortcoming. In order to achieve a more effective result with fewer complications, we have...
Fractional carbon dioxide (CO2) laser combined with subcision has been widely used for the clinical treatment, but the efficacy of the combined therapy on three types of atrophic acne scars remains unreported. This retrospective study analyzed the clinical data of 413 patients with atrophic acne scars, treated with fractional CO2 laser combined wit...
Citations
... Approximately 80.2% of patients with acne vulgaris experience various sequelae after skin lesion remission, such as facial postinflammatory erythema or postinflammatory hyperpigmentation, and approximately 43% of patients experience acne scars. 1 Acne erythema has been considered simple erythema or a vascular lesion; however, with the enhanced understanding of and histopathological insights regarding acne vulgaris, it is now considered an early scar with erythematous components. 2 Acne erythema manifests as flat or slightly depressed scars against a background of erythema with or without pigmentation 3 and is referred to as an erythematous acne scar ( Figure 1). The 1565-nm nonablative fractional laser (NAFL) has been commonly used for the early treatment of acne scars. ...
Background
Acne vulgaris is a common inflammatory disease associated with various sequelae after skin lesion remission. Acne erythema has been considered simple erythema or a vascular lesion; however, because the understanding of this disease has improved, acne erythema is currently considered an early scar with erythematous components.
Aims
This study evaluated the efficacy of using both a 595‐nm pulsed dye laser (PDL) and 1565‐nm nonablative fractional laser (NAFL) for the treatment of erythematous scars caused by acne.
Methods
Ninety patients with acne scars were equally randomized to two groups. Group A (n = 45) received treatment with the NAFL. Group B (n = 45) received treatment with the PDL and NAFL. Each patient underwent one treatment session and 4 weeks of follow‐up.
Results
Qualitative (χ² = 12.415; p < 0.05) and quantitative (t = 2.675; p < 0.05) scores of Groups A and B were determined using a global scarring grading system and exhibited statistically significant differences. The quantitative score of Group A was higher than that of Group B (6.67 ± 3.46 vs. 4.98 ± 2.44). The erythema areas of the groups differed significantly after treatment, with Group B exhibiting more notable score improvements (5.00 [3.10, 7.10] vs. 2.80 [1.65, 4.60]; Z = 3.072; p < 0.05). The erythema regression rate of Group B (88.9%) was significantly higher than that of Group A (66.7%) (χ² = 20.295; p < 0.001). Adverse events, including redness and swelling (86.6%), scabbing (78.8%), and purpura (36.6%), occurred within 7 days for 86.6% of patients.
Conclusions
The combined use of the PDL and NAFL is safe and effective for erythematous acne scars.
