Figure - available from: Dermatologic Therapy
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The wart was a gray solitary, proliferative, exophytic, nontender, 4.5 cm × 4.5 cm × 0.5 cm facial plaque with irregular margins
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Key Clinical Messase
Periungual warts are frequently encountered in the field of dermatology. Here, we describe the case of a 69‐year‐old individual who presented with hand warts. The wart growth extended to the finger stump, resulting in a soft tissue defect on the fingertip of the right thumb. A treatment approach involving superficial x‐ray ther...
Excision of warts using diode dental lasers.
Citations
Background
There are multiple treatment modalities for Periungual warts (PWs), although most are destructive and painful, limiting their application. Radiotherapy is a non-invasive method suitable for treating PW patients with contraindications to invasive procedures.
Objective
To investigate the efficacy and safety of topical Tretinoin combined with Superficial X-ray therapy (SXRT) in treating PWs.
Methods
This study included patients with 65 PWs who underwent treatment and a 3-month follow-up. 24 PWs were subjected to SXRT alone (group A). The remaining 41 PWs were subjected to SXRT combined with the application of the Tretinoin cream from the first day (group B). The overall clinical response rate, recurrence rates, cosmetic outcomes, and adverse events were observed during the follow-up period.
Results
The complete clearance rate (75% vs. 92.7% in groups A and B, respectively) and healing times (19.9 vs. 16.0 days in groups A and B, respectively) between the two groups were significantly different (P<0.046 and 0.04), indicating the combination treatment is more effective. Notably, there was no damaging or permanent deformation on the nail, and the other adverse effects were mild and bearable.
Conclusion
Topical Tretinoin combined with SXRT therapy is an effective strategy for treating PWs, with minor side effects. It is painless and with excellent cosmetic outcomes.
