Figure - uploaded by Maciej Walędziak
Content may be subject to copyright.
Source publication
Introduction:
The oxytocin challenge test (OCT) used to be one of the most important tools in assessing fetal well-being before ultrasonography became prevalent. We show that, after modifying the classification of the results and the intervention algorithm, OCT can still be a useful tool in present-day obstetrics.
Material and methods:
The study...
Context in source publication
Citations
... The key point for the prevention and treatment of postpartum uterine involution is how to promote postpartum uterine contraction, reduce postpartum hemorrhage, and reduce lochia time [34][35][36][37]. After long-term clinical practice, there are many methods for the treatment of uterine atony PPH, including surgical hemostasis and drug therapy. ...
Background. Carboprost tromethamine injection has a high safety factor in clinical application and has a good effect on uterine smooth muscle and vasoconstriction. Carboprost aminobutyriol combined with oxytocin may be beneficial to infant outcome and uterine involution after cesarean section. Objective. To investigate the effects of carboprost tromethamine combined with oxytocin on infant outcome, postpartum hemorrhage, and uterine involution in parturients undergoing cesarean section. Methods. A total of 120 parturients undergone cesarean section in our hospital from February 2019 to April 2021 were selected as the object of study. The parturients were randomly divided into control group (n=60) and research group (n=60). The control group was treated with oxytocin, and the research group was treated with carboprost aminobutyriol combined with oxytocin. The amount of maternal bleeding, uterine floor decline index, the end of lochia, poor rate of uterine involution, infant outcome, and the incidence of adverse drug reactions were compared between the two groups. Results. The amount of bleeding in the research group was significantly lower than that in the control group (P
... OCT is a test used to evaluate fetal well-being based on uterine contractions in suspected placental insu ciency. The negative OCT test was de ned as the presence of accelerations in fetal heart rate, normal variability, and absence of slowdown in uterine contractions [10]. Freeman et al. used the CST for follow-up in 679 post-term cases and observed no perinatal mortality [11]. ...
... In the study of Waledziak et al., 69 (33.8%) of 204 patients with negative OCT underwent C/S. The authors found that abnormal heart traces comprised 37.6% of C/S indications [10]. The C/S rate in our study was in agreement with study as mentioned above. ...
Purpose: To evaluate maternal and perinatal outcomes in high-risk patients who had negative OCTs and to investigate the effects of methods of induction on the development of fetal distress.
Methods: The hospital records of patients were reviewed retrospectively. Clinical data were obtained from medical records.
Results: OCT was performed in 551 patients and was negative in 447 patients. Among patients with a negative OCT, labor induction was preferred in 427 (95.5%) patients. When fetal distress development was assessed according to the induction method used following a negative OCT, and fetal distress developed in 9.1% of 427 patients who underwent labor induction.
Conclusion: When outcomes were considered in pregnant women with a negative OCT, it was observed that there were no fetal deaths and a limited number of newborns with low Apgar scores. Further randomized studies are needed to draw definitive conclusions.
With the development of precision medicine and artificial intelligence, the infusion of many drugs has been intelligently controlled according to patients’ conditions. However, the infusion of oxytocin (OT) still relies on medical staff responsible for implementing artificial regulation based on observation of fetal electronic monitoring and other maternal and fetal conditions. In this review, we discussed recent trends in intelligent infusion systems, the development status and dilemma of intelligent control of OT infusion, the drug intelligent feedback control system principle, and current risks and challenges to further promote obstetric informatization.
Objective: To compare the frequency of abnormal fetal heart rate in continuous versus discontinuous use of oxytocin infusion for augmentation of labour.
Study Design: Comparative cross sectional study.
Place and Duration of Study: Department of Obstetrics and Gynaecology, Combined Military Hospital Lahore, from Feb to Aug 2018.
Methodology: After fulfilling the inclusion criteria, 76 patients were equally divided in two groups A and B. In both groups, at 3 cm dilatation, intravenous infusion of 5 IU oxytocin in 500 cc normal saline was initiated at infusion rate 3.3mIU/minute Carditocography was initiated 10 minutes before infusion and then continued. An increment in infusion of 3.3mIU/minute was done every 20 minutes till 4 to 5 contractions in 10 minutes were achieved. After this, no more increment was done. The maximum rate was 30mIU/minute. Once cervix was 5 cm dilated, infusion was continued in group A and discontinued in group B for 2 hours. Fetal heart rate was noted on cardiotocography from 20 minutes before initiation of infusion till 2 hours after 5cm.
Results: Age of the patients was 25.4 ± 3.5 years in group A and 26.1 ± 2.4 years in group B. Mean gestation age was 39.2 ± 1.1 weeks in group A and 38.6 ± 1.3 weeks in group B. Group A had significantly more abnormal fetal heart rate compared to group B (p=0.016).
Conclusion: Discontinuous oxytocin infusion in labour showed significantly less abnormal fetal heart rate compared to continuous oxytocin infusion (p=0.016).
