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Introduction . From the perspective of evidence-based medicine, bisphosphonates (BP) represented by several drugs with various routes of administration and dosing regimens have been recognized as the gold standard for the treatment of osteoporosis (OP). Generic BPs are widely used for the treatment of OP due to the availability and optimal balance...
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A recent observational study of the incidence of pneumonia in patients with previous hip fractures found that bisphosphonate use reduced pneumonia risk by about one-quarter, in comparisons with those either not receiving osteoporosis treatment or receiving treatment with non-bisphosphonate drugs. Mortality from pneumonia was similarly reduced. It w...
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Zoledronic acid is a long-acting compound of bisphosphonate class, and it has many health and medical benefits, among which are its effects in treatment of bone disorders and accordingly decrease the incidence of osteoporosis. Besides, vitamin D is recognized as one of the fat-soluble vitamins that affect the absorption of major minerals in the dig...
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Bone material quality is important for evaluating the mechanical integrity of diseased and/or medically treated bones. However, compared to the knowledge accumulated regarding changes in bone mass, our understanding of the quality of bone material is lacking. In this study, we clarified the changes in bone material quality mainly characterized by t...