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The conversion of THs and their uptake by different types of cells with the help of membrane transporters. Where OATP1c1: (organic anion transporting polypeptide), McT8: (monocarboxylate 8 transporter), D2: (deiodinase-2), D3: (deiodinase-3), T2: (diiodothyronine). (Self-made Figure)

The conversion of THs and their uptake by different types of cells with the help of membrane transporters. Where OATP1c1: (organic anion transporting polypeptide), McT8: (monocarboxylate 8 transporter), D2: (deiodinase-2), D3: (deiodinase-3), T2: (diiodothyronine). (Self-made Figure)

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Figure. 1: The conversion of THs and their uptake by different types of...
Figure. 2: The source of THs for newly developed fetus before the onset...
Impact of thyroid hormones on brain development
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  • Aug 2022
Thyroid hormones (THs) including triiodothyronine (T3) and tetraiodothyronine (T4) perform an essential role in brain development. The active form (T3) of THs is produced after metabolism and transported in different areas of the brain. This active form interacts with different types of glial cells and stimulates the expression of various genes to...
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