| The atherosclerotic plaque. Illustration depicting the progression of plaque formation in the artery. (Top) Normal artery, with normal blood flow; (Middle) Atherosclerotic artery with plaque build-up, causing a reduced blood flow; (Bottom) Atherosclerotic artery with a ruptured plaque, causing thrombosis and blocking blood flow.

Contexts in source publication

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... no conservative significant increases were found in the atheroma from men, there were a number of proteins with more liberal significance. Amongst these, two inflammatory response proteins showed significant increases between sexes, overall and with regional differences in the plaque centre region; sPLA2-IIA and lysozyme C. It should come to no surprise that proteins related to inflammation would become a focus in a study related to atherosclerosis and indeed, inflammatory response proteins were the most discriminant functional group for the atheroma from men ( Figure 12). These have both been attributed to atherosclerotic disease. ...

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... of plasma analyses of adipokines revealed significant differences in three adipokines, including adiponectin, lipocalin-2 and resistin. When comparing the levels of adipokines from the two-points, week-0 and week-15, adiponectin levels were significantly altered in all three subgroups, control, all-RT and compliant-RT, lipocalin-2 was significantly reduced in both RT groups, and resistin was significantly reduced in the compliant-RT group ( Figure 20). ...

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... and resistin are both proinflammatory adipokines, and in the Strength study, significant decreases in plasma levels were observed in women who participated in RT (Figure 20). Lipocalin-2, also known as neutrophil gelatinaseassociated lipocalin (NGAL), is mainly produced by adipocytes in white adipose tissue. ...

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... the plasma levels at week-0 and week-15, a small significant increase in testosterone levels were observed in women in both the all-RT and compliant-RT groups. Moreover, when analysing the change-over-time values, both testosterone and SHBG levels were seen to increase significantly more in the all-RT and compliant-RT groups, respectively ( Figure 21). The observed increases in plasma testosterone levels run contradictory to most other exercise trials in postmenopausal women, which show trends to physical activity reducing testosterone levels. ...