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The association between orthostatic hypotension and cognitive impairment, dementia, Mini-Mental State Examination (MMSE) scores <18 points and MMSE scores 18-23 points in geriatric rehabilitation inpatients with standing blood pressure measurements.

The association between orthostatic hypotension and cognitive impairment, dementia, Mini-Mental State Examination (MMSE) scores <18 points and MMSE scores 18-23 points in geriatric rehabilitation inpatients with standing blood pressure measurements.

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Purpose Geriatric rehabilitation inpatients who suffer from acute and chronic diseases that aggravate blood pressure (BP) dysregulation, may be particularly susceptible to orthostatic hypotension (OH). OH may increase the risk of cerebral small vessel disease and subsequent white matter hyperintensities inducing cognitive impairment (CI). This stud...

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... OH was associated with cognitive impairment (OR=1.556, 95%CI=1.011-2.394, p=0.045) and dementia (OR=1.777, 95% CI=1.091-2.894, p=0.021), with a trend for MMSE scores <18 points (OR=1.621, 95%CI=0.944-2.782, p=0.080), after adjustment for potential confounders (Table 4, Fig. 2). Seated OH was not associated with cognition (Table ...