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A number of factors have been identified that contribute to non-adherence to medications in hypertension, one of which is the drug regimen complexity. The purpose of this study was to identify patients with poor adherence to antihypertensive therapy and compare the levels of adherence with daily dose frequency of antihypertensive therapy [Single Da...
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Context 1
... one-way ANOVA is used to determine if any of these groups reliably differ from each other on adherence level. The one-way analysis of variance (ANOVA) shown in Table 4 is used to compare the means of three categorical groups of independent variable "daily doses groups" and one continuous dependent variable with scores ranging from 1 (adherence) to 5 (poor adherence). ...Citations
Medication non-adherence is common and a primary reason for poor medical outcomes among individuals with heart failure (HF). This study's aims were to determine whether depression, hostility, and the personality-based Millon Behavioral Medicine Diagnostic (MBMD) Medication Abuse scale were associated with medication adherence (e.g., beta-blockers, ACE inhibitors, diuretics, statins) beyond contributions of demographic, medical, and psychosocial variables in an ethnically-diverse sample of 105 men and women diagnosed with HF. In hierarchical regression, greater MBMD Medication Abuse scale scores were associated with poorer adherence above and beyond both depression (β = .236, t[102] = 2.113, p = .037) and hostility (β = .244, t[102] = 2.506, p = .014). The Medication Abuse scale also completely mediated the relationship between adherence and depression. These findings suggest that personality measures such as the MBMD and hostility scales might be utilized in future studies investigating predictors of adherence and also used clinically to predict medication adherence among HF patients.
