Figure - uploaded by Bo Li
Content may be subject to copyright.
Source publication
ChemistryOpen, 2019 Mar 28;8(3):344-353
Context in source publication
Context 1
... this result into consideration, we prolonged the exposure of the cells to the compounds for 120 h. Compared with that of 72 h treatment, the IC 50 values of A13, A14, A15 were significantly decreased ( Figure 4C, Table 3, Table 4). The IC 50 values of A13, A14, A15 were 1.25 μM, 0.1 μM, 0.6 μM for A549 cells and 1.6 μM, 0.4 μM, 0.6 μM for SK-BR-3 cells, respectively. ...Similar publications
Purpose
The present study is based on screening new and potent synthetic heterocyclic compounds as anti-diabetic drugs using various computational tools, lab experiments, and animal models.
Methods
A potent synthetic compound 2-(3-benzoyl-4-hydroxy-1,1-dioxido-2H-benzo[e][1,2]thiazin-2-yl)-1-(2-bromophenyl) acetamide (FA2) was checked against diab...
