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The Gomco Clamp showing components, in a range of sizes, that are assembled during the procedure described in the text. Procedure: First of all, a dorsal slit is made in the foreskin and the foreskin is separated from the glans. The bell of the Gomco clamp is then placed over the glans, and the foreskin is pulled over the bell. The base of the Gomco clamp is placed over the bell, and the Gomco clamp's arm is fitted. After the surgeon confirms correct fitting and placement (and the amount of foreskin to be excised), the nut on the Gomco clamp is tightened, causing the clamping of nerves and blood flow to the foreskin. The Gomco clamp is left in place for about 5 minutes to allow clotting of blood to occur, then the foreskin is dissected off using a scalpel. The Gomco's base and bell are then removed, and the penis is bandaged. It is a fairly bloodless circumcision technique. The circumcision is relatively quick compared to the Plastibell. It was the most popular method for circumcisions between 1950 and 1980 and is still common today, especially in the USA. A training video of a neonatal Gomco circumcision using dorsal penile nerve block and a sucrose pacifier, conducted by Dr Richard Green, Stanford University School of Medicine, is available at  Dr Sam Kunin, an experienced urological surgeon in Los Angeles, has developed a clever, and very effective, method in which local anaesthetic is injected into the distal foreskin (Kunin, 2007b). Doing so separates the inner and outer foreskin therefore allowing the inner layer to be pulled against the bell of the Gomco clamp, and results in a maximum amount of inner layer being removed (). He points out that the inner lining is the area most prone to adhesions, irritations, yeast and bacterial infections, particularly in diabetics. Gomco clamps exist in sizes from neonatal to adult. Suturing is required post-infancy. 

The Gomco Clamp showing components, in a range of sizes, that are assembled during the procedure described in the text. Procedure: First of all, a dorsal slit is made in the foreskin and the foreskin is separated from the glans. The bell of the Gomco clamp is then placed over the glans, and the foreskin is pulled over the bell. The base of the Gomco clamp is placed over the bell, and the Gomco clamp's arm is fitted. After the surgeon confirms correct fitting and placement (and the amount of foreskin to be excised), the nut on the Gomco clamp is tightened, causing the clamping of nerves and blood flow to the foreskin. The Gomco clamp is left in place for about 5 minutes to allow clotting of blood to occur, then the foreskin is dissected off using a scalpel. The Gomco's base and bell are then removed, and the penis is bandaged. It is a fairly bloodless circumcision technique. The circumcision is relatively quick compared to the Plastibell. It was the most popular method for circumcisions between 1950 and 1980 and is still common today, especially in the USA. A training video of a neonatal Gomco circumcision using dorsal penile nerve block and a sucrose pacifier, conducted by Dr Richard Green, Stanford University School of Medicine, is available at Dr Sam Kunin, an experienced urological surgeon in Los Angeles, has developed a clever, and very effective, method in which local anaesthetic is injected into the distal foreskin (Kunin, 2007b). Doing so separates the inner and outer foreskin therefore allowing the inner layer to be pulled against the bell of the Gomco clamp, and results in a maximum amount of inner layer being removed (). He points out that the inner lining is the area most prone to adhesions, irritations, yeast and bacterial infections, particularly in diabetics. Gomco clamps exist in sizes from neonatal to adult. Suturing is required post-infancy. 

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... 7 8 Male circumcision provides significant protection against HIV transmission and other sexually transmitted infections (STIs) in men. [9][10][11][12][13][14][15] This has been proven by randomised controlled trials in South Africa, Kenya and Uganda, 13 16 17 showing that circumcised males were less likely to become infected with HIV. As a result, male circumcision is increasingly recommended as a strategy to reduce HIV transmission, particularly in areas with a high prevalence of HIV. ...
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... The excess foreskin was trimmed from around the bell using iris scissors. The handle was then broken off the device (11) .  Thermal assisted circumcision (Group C) : ...
... Despite the heated controversy, circumcision during infancy may offer a "window of opportunity" since it may be linked with reduced expenses, a decreased risk of complications when carried out in a suitable setting by a skilled practitioner, and a less negative psychological impact on the kid. Additionally, because infants are less active than adults, the treatment may be done on them while they are under local anesthetic (11) . Additionally, male circumcision during the first year of life was advised by El Bcheraoui et al. (19) and Bicer et al. (20) because to the very low occurrence of adverse effects, which may increase up to 10-20 folds when performed beyond infancy. ...
... Major indications of circumcision include the religion, cultural, medical and recently public health reasons. [1,2] Circumcision has many other benefits such as protection against penile cancer, recurrent urinary tract infection, balanitis and sexually transmitted diseases. [3][4][5] Male circumcision is almost universal in our valley of Kashmir due to recommended practice of Islamic culture by Muslims. ...
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Background Circumcision has been one of the most commonly performed surgical procedures worldwide since ancient times. Given the popularity of this procedure, the aim of this study was to evaluate the effectiveness, reliability, and results of circumcision performed using the NeoAlisTM clamp and compare them with those obtained using the sleeve technique. Study design The results of 2259 patients circumcised using the two techniques were evaluated retrospectively. The patients who were circumcised using the plastic NeoAlisTM device were classified as group 1 and those circumcised using the sleeve technique were designated as group 2. The groups were compared in terms of operation time, results, cost, complications, and cosmetic satisfaction scores. Results A total of 1947 patients who met the inclusion criteria were included in the study. Group 1 consisted of 1454 patients, while group 2 comprised 493 patients. The total rate of complications, excluding bleeding in the form of oozing that stopped spontaneously, was 9.5% (n = 185). In group 1, the operation time was shorter, tolerability of local anesthesia was higher, satisfaction questionnaire scores were higher, cost was lower, and rates of early adhesion and meatal stenosis were lower. All of these parameters were significantly different from those in group 2. Notably, secondary phimosis was significantly higher in group 1. Although the bleeding that stopped with follow-up was significantly higher in group 2, there was no significant difference between the groups in terms of bleeding that required surgical intervention. Discussion Our study, which reports the results of circumcisions performed using the NeoAlis clamp, has the largest sample size in the literature. Moreover, this is the only study in the literature wherein the results of sleeve circumcision, which is a time-tested surgical procedure, and the results of NeoAlis clamp circumcision, which we applied to a large number of patients, were compared with each other and with the literature. The retrospective design that focused on relatively short-term (one month) results is the major limitation of this study. Conclusion Mass circumcision performed with a plastic clamp technique is safe, timesaving, easily teachable, and cosmetically advantageous.
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... It is expected that laser/cautery method resulted in lower post-circumcision complications. 3,4,5 Tenascin-c is first discovered in muscle tissue and nervous system more than 20 years cellular signaling. These abilities are mediated through activation of pro-inflammatory cytokines and oncogenic signaling molecules. ...
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Introduction In the era of personalized health, the quest for biomarker as tools of examination, of diagnosis and of follow up deemed necessary. In this study, the author analyzed the outcome of skin tissue repair dorsal-slit and laser (cauterization) through expression of tenascin-C. (TNC) is an extracellular glycoprotein expressed during embryogenesis and markedly increased in wound healing, especially in resolution phase. Methods This study was conducted from July 2015 until May 2016 at Histology Lab FMUI and obtained ethical clearance from FMUI ethical committee no 751b/UN2.F1/ETIK/VIII/2015. Prepuces from 20 male participants (5-12 years old) were collected under signed informed consent and stained using hematoxylin-eosin staining to determine incisional margin area. Tenascin-C expression was determined by immunohistochemistry with ratio of TNC positive area and incisional margin area. Follow-up investigation was done using post-operative questionnaire and photographs to determine the status of wound healing. Result The conventional group showed greater TNC expression (57.28± 47.56%) than cauterization group (25.36 ± 16.44%) (p=0.07). The mean expression of TNC in normal wound healing subjects (42.15 ± 40.87%) is slightly more than the mean of delayed wound healing subjects (38.83 ± 33.40%) (p=0.872). The number of subjects with normal healing after cauterization or conventional techniques is almost identical. Conclusion The data presented here suggested that higher TNC expression indicate a trend toward normal wound healing. Further study with larger sample number is required. Keywords: Circumcision, dorsal-slit, cauterization, tenascin-c, wound healing
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