Figure 1
The CT angiography of the patient with pulmonary embolism; embolism is observed in the both left and right pulmonary arteries.
Source publication
Introduction: COVID-19 is an emerging disease that has been spread all over the world. Not all the dimensions and manifestations of the disease have yet been fully explored. One such manifestation is vascular thrombosis that occurs in the lungs and other vessels. However, it is often ignored or mistaken for pulmonary manifestations. Herein, we pres...
Context in source publication
Context 1
... to the progressive nature of the respiratory symptoms, the computed tomography and CT angiography (CTA) of pulmonary veins were performed. CTA revealed massive pulmonary embolism at the beginning of the left and right pulmonary arteries, and compatible pneumonia presentation was observed ( Figure 1). Echocardiography showed a large RV mass, PAP = 53 mmHg, and severe RV dysfunction. ...
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Background
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Objective:
Cytokine storm with elevated levels of multiple proinflammatory cytokines and inflammatory system activation underlie the pathogenesis of coronavirus disease 2019 (COVID-19). In this study, we aimed to investigate whether increased interleukin (IL)-6 levels can predict right ventricular (RV) systolic impairment in patients hospitalized...
Purpose of Review
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Citations
... An increase in D-dimer (> 1 mg/ dL) is not a reliable indicator of venous thromboembolism [6,22], although it may result in mortality. As a result, CT angiography can be helpful in diagnosing VTE in patients with coronavirus [23]. Developing PE have been associated with several risk factors including hypertension, coronary heart disease, malignancy, etc. [24]. ...
There is some recent evidence that the coronavirus disease 2019 (COVID-19) increases the risk of venous thromboembolism by creating a prothrombotic state. COVID-19 and pulmonary embolism (PE) are both associated with tachypnoea, hypoxemia, dyspnoea, and increased D-dimer. Diagnosis of pulmonary embolism in a patient with COVID-19 compared to an individual without it, using the conventional clinical and biochemical evidence is challenging and somehow impossible. In this study, we reported four male cases affected by COVID-19 and admitted to hospitals in Sanandaj, Iran. The patients were all older adults (ranging between 56 and 95 years of age). Fever, chills, muscle pain, and cough were evident in all the cases. Red blood cell levels were low, and pulmonary embolism was clearly detected on spiral computed tomographic (CT) angiography of the pulmonary circulation of all patients. These cases demonstrated that COVID-19 may lead to pulmonary embolism by causing blood coagulation problems. As COVID-19 continues to cause considerable mortality, more information is emerging which reveals its complicated pathogenicity. In the meantime, venous thromboembolism remains an uncommon finding in patients with COVID-19. It is essential that health care providers perform the necessary diagnostic evaluations and provide appropriate treatment for patients.
... An increase in D-dimer (> 1 mg/dL) may indicate mortality in these patients but is not a reliable indicator in the diagnosis of venous thromboembolic [5,20]. As a result, CT angiography can be helpful in diagnosing VTE in patients with coronavirus [21]. ...
Recently, there is evidence that the coronavirus disease 2019 (COVID-19) increases the risk of venous thromboembolism by creating a prothrombotic state. COVID-19 and pulmonary embolism (PE) are both associated with tachypnoea, hypoxemia, dyspnoea, and increased D-dimer. Diagnosis of pulmonary embolism in a patient with COVID-19 compared to a patient without it using the conventional clinical and biochemical evidence is challenging and somehow impossible. In this study, we report 4 male cases affected by COVID-19, admitted to hospitals in Sanandaj, Iran. The patients were all older adults (ranged between 56 and 95 years of age). Fever, chills, muscle aches, and cough were evident in all of them. Red blood cell levels were low, while pulmonary embolism was clearly seen on spiral computed tomographic (CT) angiography of the pulmonary circulation of all patients. These cases demonstrated that COVID-19 may lead to pulmonary embolism by causing blood coagulation problems. As COVID-19 continues to cause considerable mortality, more information is emerging which reveals its complicated pathogenicity. In the meantime, venous thromboembolism remains an uncommon finding in patients with COVID-19. It is essential that health care providers perform the necessary diagnostic evaluations and provide appropriate treatment for patients.
There is ample evidence that the coronavirus can cause fatal blood clots. Angiotensin-converting enzyme 2 (ACE2) receptors act as a gateway for the coronavirus to enter the body and facilitate infection. ACE2 receptors are scientifically linked to disease severity in smokers because nicotine is thought to affect ACE2 expression in different ways.
Patients admitted with severe COVID-19 infection with high levels of factor V Leiden are prone to serious damage from blood clots such as deep vein thrombosis or pulmonary embolism.
Damage to the vascular endothelium is a complication that can be caused by the coronavirus. It can cause vascular clots, in the formation of which factors such as age, sex, blood type, and underlying diseases are effective. Thrombotic events, especially venous thrombosis, following COVID-19 infection have already been described; nonetheless, data are scarce on arterial thrombosis.
