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Superimposition intraoral scanner (IOS) þ face scanner (FS) þ cone beam computed tomography (CBCT). (A) CBCT images obtained with CS 9300 (Carestream Dental, Rochester, NY), visualized in the proprietary software of the device, and imported in the Mimics (Materialise, Leuven, Belgium) software, for 3D bone reconstruction. (B) Intraoral digital impression with CS 3600 (Carestream Dental), lateral, frontal, and occlusal views, file format .PLY. (C) Face scans with OBI (Mede SA, Lugano, Switzerland), frontal, and lateral views, file format .OBJ. (D) Superimposition of the intraoral digital impression (.PLY) on the face scan (.OBJ), to obtain the 3D virtual dentate patient, lateral views. The software used for the superimposition is Meshlab (an open source software). (E) 3D bone reconstruction and implant planning (Mimics, Materialise), superimposition of the IOS files on the 3D bone reconstruction, design of the surgical guide (Lynx, Gioia del Colle, Italy). (F) Guided implant surgery with flap elevation and bone regeneration with synthetic porous hydroxylapatite. (G) Intraoral digital impression with CS 3600 (Carestream Dental), occlusal and lateral views, file format .PLY, and prosthetic planning with Exocad (Fraunhofer Institute, Frankfurt, Germany). (H) Finalization of the patient. 

Superimposition intraoral scanner (IOS) þ face scanner (FS) þ cone beam computed tomography (CBCT). (A) CBCT images obtained with CS 9300 (Carestream Dental, Rochester, NY), visualized in the proprietary software of the device, and imported in the Mimics (Materialise, Leuven, Belgium) software, for 3D bone reconstruction. (B) Intraoral digital impression with CS 3600 (Carestream Dental), lateral, frontal, and occlusal views, file format .PLY. (C) Face scans with OBI (Mede SA, Lugano, Switzerland), frontal, and lateral views, file format .OBJ. (D) Superimposition of the intraoral digital impression (.PLY) on the face scan (.OBJ), to obtain the 3D virtual dentate patient, lateral views. The software used for the superimposition is Meshlab (an open source software). (E) 3D bone reconstruction and implant planning (Mimics, Materialise), superimposition of the IOS files on the 3D bone reconstruction, design of the surgical guide (Lynx, Gioia del Colle, Italy). (F) Guided implant surgery with flap elevation and bone regeneration with synthetic porous hydroxylapatite. (G) Intraoral digital impression with CS 3600 (Carestream Dental), occlusal and lateral views, file format .PLY, and prosthetic planning with Exocad (Fraunhofer Institute, Frankfurt, Germany). (H) Finalization of the patient. 

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Purpose: The aim of this literature review was to provide an update on the current scientific knowledge in the field of 3D virtual patient science and to identify a possible easy, smart, and affordable method to combine different file formats obtained from different digital devices. Methods: Electronic searches of the Medline database was perfor...

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... PEEK is a biocompatible, nonallergic, rigid, radiolucent, white polymer with low plaque affinity [28] and elastic modulus that is close to human bone [29]. Some recent studies have reported on the use of PEEK as a bar fabrication material 5 Case Reports in Dentistry with promising results [30] that must be further investigated. Another aesthetic material incorporated in many dental applications is zirconia [31], a biocompatible ceramic material with wear resistance and high mechanical properties. ...
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Objectives To evaluate the correlation of measures of periodontal defects in 3D models segmented by an AI-driven tool with the actual defects in dry skulls and mandibles and to verify the influence of arch, presence of metal artifact (dental fillings/metal posts), type of defect and dental implant artifact on the measures. Material and Methods 45 periodontal defects were measured with a digital caliper and periodontal probe in three human dried skulls and five mandibles. These skulls and mandibles were scanned with a Cone-Beam Computed Tomography (CBCT) device and their digital files followed automated segmentation by an AI-driven tool (Patient Creator, Relu BV, Leuven, Belgium). The same periodontal defects were measured on the digital model generated by the AI-tool. Correlations of the measuring methods were assessed by means of Intraclass Correlation Coefficient and the influence of arch, presence of artifact and type of defects on the differences were assessed by Student’s t-test. Results The intraclass correlations ranged from moderate to excellent values. None of the studied factors (arch, dental fillings/metal posts and type of defect) played a role on the differences between actual and digital defects (P > 0.05). Three-wall defects presented significant influence of dental implant artifact on the measures of height (P = 0.002). Conclusions 3D models generated by the AI-driven tool presented periodontal defects with linear measures ranging from moderate to excellent correlations with the actual measures.