Summary of validation parameters of proposed RP-HPLC method

Summary of validation parameters of proposed RP-HPLC method

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This paper describes a high-performance liquid chromatographic method for simultaneous estimation of nabumetone and paracetamol in binary mixture. The method was based on RP-HPLC separation and quantitation of the two drugs on hypersil C-18 column (250 mm × 4.6 mm) using a mobile phase consisting of acetonitrile and 0.05% aqueous acetic acid (70:30...

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... method was found to be accurate and precise, as indicated by recovery studies and % RSD not more than 1.5. The summary of validation parameters of proposed HPLC method is given in Table 3. ...

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