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Summary of laboratory test results carried out as part of the differential diagnosis in a patient with rheumatoid arthritis. a

Summary of laboratory test results carried out as part of the differential diagnosis in a patient with rheumatoid arthritis. a

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A 49-year-old man presented at a hospital with an arthritic flare-up and stress dyspnea with a cough. He had a 5-year history of symmetrical polyarthritis, for which he was prescribed 5-15 mg prednisolone daily. He was subsequently diagnosed with rheumatoid arthritis and prescribed 20 mg methotrexate weekly, 3 mg/kg ciclosporin daily and 5 mg predn...

Contexts in source publication

Context 1
... had 20 swollen and tender joints, and scored 1.5 on a HEALTH ASSESSMENT QUESTIONNAIRE (HAQ) and 5.6 on the DISEASE ACTIVITY SCORE (DAS). Laboratory analyses revealed elevations in the patient's erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), lipid levels and white-blood-cell count (Table 1). His kidney and liver function were normal. ...
Context 2
... kidney and liver function were normal. A panel of laboratory assays to detect rheumatoid factor, ANTICARDIOLIPIN ANTIBODY, antinuclear anti- body, anti-β2-glycoprotein I antibodies and LUPUS ANTICOAGULANT (LA) yielded negative results (Table 1). No significant cardiac abnor- malities were detected on electrocardiography and clinical investigation. ...
Context 3
... patient had 18 swollen and tender joints, a HAQ score of 1.5, a DAS of 5.41, an ESR of 50 mm/h and a CRP level of 136.4 mg/l. His levels of creatinine kinase-MB and troponin were within normal range (Table 1). Echocardiography demonstrated cardiac wall-motion abnormalities with anteroseptal hypokinesis, but the chamber dimensions, ejection fraction and diastolic func- tion of the left ventricle were normal (Figure 1). ...
Context 4
... tests for hereditary coagulation factors, anticar- diolipin, anti-β glycoprotein antibodies, tissue thromboplastin inhibition and kaolin clotting time yielded normal or negative results, the patient's DILUTE RUSSELL VIPER VENOM TIME (DRVVT) and DRVVT ratio were higher than normal, indicating the presence of LA. Assays for rheumatoid factor, anticitrullinated peptide, antinuclear antibodies and anti-double-stranded DNA antibodies were all negative ( Table 1). ...

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