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Structures of some important aminocyclitols.
Source publication
The efficient synthesis of two new stereoisomeric 3-aminocyclooctanetriols and new halocyclitol derivatives of them starting from cis,cis -1,3-cyclooctadiene are reported. Reduction of cyclooctene endoperoxide, obtained by photooxygenation of cis,cis -1,3-cyclooctadiene, with zinc yielded a cyclooctene diol followed by acetylation of the hydroxyl g...
Context in source publication
Context 1
... aminocyclitols and their derivatives have been found to possess antibiotic properties, such as validamycins (1) [16]. Validamycin A (1) contains two aminocyclitol units, one valienamine (2) and the other validamine (3) (Figure 1). One of the most important conduramines (4) is valienamine (3) [17], is found as a building block in several aminoglycoside antibiotics [2]. ...
Similar publications
The efficient synthesis of two new stereoisomeric 3-aminocyclooctanetriols and their new halocyclitol derivatives starting from cis,cis -1,3-cyclooctadiene are reported. Reduction of cyclooctene endoperoxide, obtained by photooxygenation of cis,cis -1,3-cyclooctadiene, with zinc yielded a cyclooctene diol followed by acetylation of the hydroxy grou...