Figure - available from: Molecular and Cellular Biochemistry
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Small intestinal mucosal biopsy from a patient without type 2 diabetes (T2D) stained for chromogranin-A (a) and for neurotensin (b). Small intestinal mucosal biopsy from a patient with T2D stained for chromogranin-A (c) and for neurotensin (d). Arrows indicate some stained cells. Comparison of the stained area for neurotensin in the small intestine of subjects with obesity without and with concomitant T2D (e). Statistical analysis: *p < 0.05
Source publication
Neurotensin (NT) is a gastro-intestinal hormone involved in several pathways that regulate energy and glucose homeostasis. NT was hypothesized to act in synergy with incretin hormones to potentiate its anti-diabetic effects. Additionally, circulating NT levels were shown to rise after bariatric surgery-induced weight loss. Knowledge of NT-secreting...
