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PurposeForeign body aspiration is very common in paediatric age group specially 6 months to 4 years of age, but it is relatively unusual entity amongst adult population unless predisposing factor like alcohol or drug intoxication or psychiatric illness.We are reporting a case of foreign body (sewing needle) aspiration which penetrated through thyro...
Context in source publication
Context 1
... ingestion of sewing needle while doing sewing work after her din- ner 1 h back followed by neck swelling, pain and haemoptysis. On examination patient was anxious but haemodynamical- ly stable. Single 5 · 5 mm sized pointed midline neck swelling was seen at the level of thyroid cartilage. Skin overlying the swelling was intact (Fig. ...Citations
... [2] In India, it is the seventh most common cancer in males [3,4] and accounts for approximately 2% of all cancers. [5,6] Apart from the general symptoms of laryngeal carcinoma including complete airway obstruction, severe respiratory distress, and the inability to speak, [7][8][9] one of the hallmarks of laryngeal cancer is distant metastasis which decreases survival by almost 50%, and its further invasion beyond the lymph nodes makes the situation worst. [10][11][12] Matrix metalloproteinases (MMPs) are a collection of enzymes capable of cleaving extracellular matrix components which are a key factor for invasion and metastasis. ...
Aim of the study:
Both matrix metalloproteinase-2 (MMP-2) and matrix metalloproteinase-9 (MMP-9) is involved in degradation of extracellular matrix and found to stimulate invasion and metastasis in cancer patients. However, studies on the stage-specific expression of MMPs at different stages of larynx carcinoma are still lacking. In the present study, we compare the expression level of MMP-2 and MMP-9 at different stages of laryngeal carcinoma.
Material and methods:
Tumor tissues samples were taken from larynx cancer patients by deep biopsy during direct laryngoscopy. Gene expression for MMP-2 and MMP-9 was analyzed using RT-PCR.
Results:
Significantly high expression of MMP-2 was observed compared to the MMP-9 at stage IV compared to the less advanced stages of the disease.
Conclusion:
Present study concluded that the MMP-2 expressed with a greater magnitude as compared to the MMP-9 in advance stages of laryngeal carcinoma.
... [1] Precipitating factors noted in adult foreign body ingestion are dental procedures, neurological dysfunction, mental retardation, edentulous, seizures and alcoholism. [2] Patients presented with odynophagia, after accidental ingestion. Trial of removal can be done under direct or endoscopic vision in a clinical setting, failing which, removal can be attempted under general anaesthesia. ...
Foreign body ingestion is a common otorhinolaryngological emergency encountered. Most frequently noted are fish bones, which usually get impacted at the level of cricopharynx. However, sometimes few may migrate extraluminally, or even extrude subcutaneously. We present a case of an adult with foreign body ingestion (fish bone) which had migrated and embedded in the left pyriform sinus and larynx, requiring open surgery for removal.
Objective: To report a case of crab shell impaction at the glottic level presenting only as aphonia and cough.
Methods
Design: Case Report
Setting: Tertiary Government Hospital
Patient: One (1)
Results: A 36-year-old male, who presented in emergency with sudden aphonia after a meal, was found to have crab shell with leg spines impacted at the glottic level. Due to its large size, ragged edges and the sharp spines stuck in the tissue, endoscopic removal needed a prior tracheostomy. All pieces were extracted, with no bleeding, laceration or tissue damage. The patient completely recovered with normal vocal folds and a normal voice at follow up.
Conclusion: Our experience suggests that an impacted foreign body may warrant a tracheostomy to secure the airway prior to extraction, and avoid any possible complications including laryngeal injury.
Keywords: foreign body, larynx, crab shell, loss of voice
