Semithin sections stained with toluidine blue of the sciatic nerve. a-Normal neural morphology in SHAM group, b-Note that the swollen appearance of the axons and the decrease in number of axons with intact myelin sheath in CCI group, cMarked regeneration of axons of CCR1w group, d,e-Less marked recovery of the neural structures in CCR3w and CCR5w group, respectively (Bar: 10 µm) Şekil 1. Siyatik sinirin toluidin mavisi ile boyanmış yarı ince kesitleri. a-SHAM grubunda normal noral morfoloji, b-CCI grupta aksonların şişmiş görünümü ve intakt miyelin kılıflı aksonların sayısında azalma, c-CCR1w grubunda aksonların belirgin rejenerasyonu, d,e-Sırasıyla CCR3w ve CCR5w gruplarında noral yapının daha az belirgin düzelmesi (Bar: 10 µm)

Contexts in source publication

Context 1

... microscopic findings showed the normal structural features in the SHAM animals. Myelinated axons of sciatic nerve was normal in appearance and a few unmyelinated axons were observed (Fig. 1a). After CCI, axonal damage and thinly myelin sheaths were increased and common decrease was seen in the number of myelinated axon. Some areas with a depletion of nerve fibers were also shown (Fig. 1b). One week after decompression, significant increase in the number of myelinated axon was observed and only a few degenerated fibres were ...

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... structural features in the SHAM animals. Myelinated axons of sciatic nerve was normal in appearance and a few unmyelinated axons were observed (Fig. 1a). After CCI, axonal damage and thinly myelin sheaths were increased and common decrease was seen in the number of myelinated axon. Some areas with a depletion of nerve fibers were also shown (Fig. 1b). One week after decompression, significant increase in the number of myelinated axon was observed and only a few degenerated fibres were determined. Remyelinised axons were also abundant (Fig. 1c). After the third week, several degrees of axonal injury were seen and its progression to myelinated fiber degeneration are shown. ...

Context 3

... sheaths were increased and common decrease was seen in the number of myelinated axon. Some areas with a depletion of nerve fibers were also shown (Fig. 1b). One week after decompression, significant increase in the number of myelinated axon was observed and only a few degenerated fibres were determined. Remyelinised axons were also abundant (Fig. 1c). After the third week, several degrees of axonal injury were seen and its progression to myelinated fiber degeneration are shown. Degenerated myelin fibres increased from the third to fifth week decompression. Morphological signs of axonal regeneration were reduced remarkably ( Fig. 1d-e). DRGs associated both in the control and CCR1w ...

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... were determined. Remyelinised axons were also abundant (Fig. 1c). After the third week, several degrees of axonal injury were seen and its progression to myelinated fiber degeneration are shown. Degenerated myelin fibres increased from the third to fifth week decompression. Morphological signs of axonal regeneration were reduced remarkably ( Fig. 1d-e). DRGs associated both in the control and CCR1w animals showed compact and regularly arranged structures (Fig. 2a-c). After CCI, the major pathological change was that of microvacuolisation of the DRG cells (Fig. 2b). In addition, cell membrane lines were lost and their sizes were larger. These changes were seen in CCR3w and CCR5w ...