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The experiment was conducted on 90 Karacabey Merino ewes divided into three groups. The first group of ewes was treated with 5 mL 0.1% sodium selenate, the second with 5 mL 0.1% sodium selenate and 250 mg vitamin E, while the third one was a control group. The effect of intra-muscular injection of selenium (Se) and Se plus vitamin E on oestrus, fer...
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Forty-two 7-mo-old Australian Merino wethers were used in a 50-d trial to investigate the effects of Se and vitamin E on the performance and physiological responses of heat-stressed sheep. Sheep were exposed to thermoneutral conditions (maximum = 24°C and minimum = 20°C) for 28 d followed by heat (maximum = 38°C and minimum = 28°C) for 22 d. Hot co...
The aim of this study was to determine effects of liquid supplement of vitamin E and Selenium (Certiselen E ®) on performance and immune response of laying hens during high environmental temperature. A total number of 144 white Lohman LSL-Lite laying hens at 63 weeks of age divided into 24 cages. Four levels of Certiselen-E supplement including zer...
This study evaluated the effect of supplemental vitamin E to ewes in late pregnancy on the rate of stillborn lambs. Ewes in 19 flocks in 5 regions of Norway were daily supplemented the 6-7 weeks before average expected lambing date with either 1) 360 IU of vitamin E (supplemented), or 2) placebo (control). The daily supplement was given in addition...
Koyuncu, M., Kara Uzun, Ş., Öziş, Ş. and Yerlikaya, H. 2006. Effects of selenium-vitamin E or progestagen- PMSG injections on reproductive performance of ewes. J. Appl. Anim. Res., 29: 137–140.The experiment was conducted on 120 Karacabey Merino ewes divided into four groups. Two groups consisted of 2-year-old ewes, before their first lambing and t...
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Citations
... Vitamin E is a crucial lipid-soluble antioxidant that can reduce hydrogen peroxide formation and prevent oxidative damage to the sensitive membrane lipids, thereby reducing oxidative stress and maintaining the integrity of cell membranes [17]. Vitamin E can also prevent peroxidation in the susceptible subcellular membrane [18]. Selenium (Se) acts as antioxidant factor because it is a crucial component of the glutathione peroxidase enzymes, which may eliminate lipid hydroperoxides and hydrogen peroxide (H 2 O 2 ) [19]. ...
Background
Nutrition has a primary role for optimum expression of genetic potential, and most of the farmers have limited resources of green fodder. Hence, a fat-soluble vitamin, especially vitamin A and E and trace elements remained most critical in the animal’s ration and affects their productive and reproductive performance adversely. Animals cannot be able to produce these vitamins in their bodies; hence, an exogenous regular supply is needed to fulfil the physiological needs and to maintain high production performance. This study elucidated effects of antioxidant vitamins (A, D, E) and trace elements (Cu, Mn, Se, Zn) administration on gene expression, metabolic, antioxidants and immunological parameters in dromedary camels during transition period.
Results
At 0 day, there were no appreciable differences in the expression patterns of the metabolic (IGF-I, ACACA, SCD, FASN, LPL, and BTN1A1) genes between the control and treatment groups, despite lower levels. A substantial variation in the mRNA levels of SOD1, SOD3, PRDX2, PRDX3, PRDX4, PRDX6, and AhpC/TSA was observed between the control and treatment groups, according to the antioxidant markers. In comparison to the control group, the treatment group displayed a significant up-regulation at 0 and 21 days. The treatment and control groups exhibited substantial differences in the mRNA values of IL-1α, IL-1β, IL-6, and TNFα, as indicated by immunological markers. In comparison to the control group, there was a noticeable down-regulation in the treatment group at 0 and + 21 days. But IL10 produced the opposite pattern. No significant difference was observed in glucose, cholesterol, triglyceride, HDL, total protein, NEFA, BHBA, cortisol and IGF-1 levels between control and treatment group. The activity of serum GPx, SOD and TAC was significantly affected by time and treatment x time in supplemented groups as compared with control group. IL-1, IL-1, IL-6, and TNF were noticeably greater in the control group and lower in the treatment group. Additionally, in all groups, the concentration of all pro-inflammatory cytokines peaked on the day of delivery and its lowest levels showed on day 21 following calving. The IL-10 level was at its peak 21 days prior to calving and was lowest on calving day.
Conclusion
The results demonstrated a beneficial effect of antioxidant vitamins and trace elements on the metabolic, antioxidant and immunological markers in dromedary camels throughout their transition period.
... Explanations: G1 -Bakofix ® treatment seven days before estrus synchronization; G2 -Bakofix ® treatment on the day of initiation of estrus synchronization; G3 -no Bakofix ® treatment; * P < 0.05, *** P < 0.001 Merino sheep showed that selenium or selenium + vitamin E treatment did not have a significant effect on the pregnancy rate, but led to an increase in fecundity (13). Similarly, in another study on sheep, Vitamin E or Vitamin E + selenium treatment was found to have a positive effect on estrus response, pregnancy rate, and fecundity (2,23). ...
This study investigated the effect of Bakofix® (a supplement consisting of vitamin E, copper, zinc, manganese, cobalt, selenium, and calcium) on the reproductive performance of Anatolian Merino sheep. A total of 80 clinically healthy sheep were used in the study. They were synchronized with a progesterone-containing sponge outside the breeding season and divided into three groups. The first group (G1, n = 25) was administered Bakofix® treatment 7 days before estrus synchronization, the second group (G2, n = 25) was administered Bakofix® treatment when estrus synchronization began, and the third group served as the control (G3, n = 30). G1 showed a higher estrus response, conception rate, and pregnancy rate compared to the other groups. Particularly remarkable was the 84% pregnancy rate obtained in G1. The fecundity and litter size in G1 were 2.4 and 2.8, respectively, which were higher than those in the other groups. The multiple birth rate in G1 was significantly higher than that in G3, and Bakofix® treatment seven days before synchronization had a positive effect on the multiple birth rate, with a statistically significant difference between the two groups (P < 0.05). Although the multiple birth rate was high in G1, the birth weights of the lambs were not negatively affected. In conclusion, vitamin, mineral, and trace element supplementation can be applied to increase the reproductive performance of Anatolian Merino ewes, especially outside the breeding season and before estrus synchronization, which can lead to increased economic gain.
... Table 3 demonstrated that Group 1 exhibited a significant increase in the time of the first appearance of estrus and the average time for estrus to occur compared to Group 2. On the other hand, Group 2 showed a significant increase in estrus rate compared to Group 1 and Group 3. The higher estrus rate observed in the second group may be attributed to the role of selenium in improving follicle growth and maturation, which consequently has a positive impact on estrogen secretion from mature follicles and the manifestation of estrus signs. This study is consistent with the findings of [22], who reported that injecting merino ewes with selenium before the start of the reproductive season and prior to parturition resulted in increased estrus, fertility, and successful delivery. Table 3 revealed that Group 2 exhibited a significant increase in fertility rate, fertilization rate, and pregnancy rate compared to Group 1 and Group 3. Additionally, both Group 2 and Group 3 showed a significant increase in fertility rate, fertilization rate, and pregnancy rate. ...
This study was conducted at the animal farm affiliated with the college of agriculture, university of anbar, ramadi, iraq, to investigate the effects of selenomethionine or selenium-enriched yeast on the reproductive performance and hormone levels (progesterone and estrogen) in Iraqi ewes. the study was carried out from July 26, 2022, to january 27, 2023. eighteen ewes with an average age of 2-3 years and an average body weight of 43 ± 2.5 kg were used. the ewes were randomly divided into three equal groups, with six ewes in each group. all ewes were fed the same ration. group 1 served as the control group and received no treatment, while group 2 was treated with selenomethionine at a dose of 0.03 g/kg/bw. group 3 was treated with selenium-enriched yeast (saccharomyces cerevisiae-selenium) at the same dose, following the guidelines of the national research council (nrc, 1980). the treatments were administered orally for 45 days by dissolving the samples in 30 ml of distilled water. blood samples were collected from the jugular vein to assess changes in hormone concentrations. the results showed a significant increase in progesterone levels during the second period for groups 1 and 2 compared to group 3 (p ≤ 0.01). group 1 exhibited a significant increase in the time of the first appearance of estrus and the average time for estrus compared to group 2. group 2 showed a significant increase in estrus rate compared to group 1 and group 3. both group 2 and group 3 exhibited a significant increase in fertility rate, fertilization rate, pregnancy rate, and lambing rate. group 2 and group 3 also showed a significant increase in fecundity, twinning rate, and litter size compared to group 1. In conclusion, the supplementation of Selenomethionine and Selenium-enriched yeast positively affected reproductive performance in Iraqi ewes, as evidenced by improved hormone levels, estrus characteristics, fertility rates, and lambing outcomes.
... Vitamin and mineral supplementation is also used to increase fertility during synchronization. According to research, sheep bred in areas where dry grass and grain stubble are fed may benefit from the addition of vitamins A, E, D3, and selenium, especially during breeding season (Chew, 1993;Boland et al., 2005;Koyuncu and Yerlikaya, 2007;Köse et al., 2013;Yeşil and Sarıözkan, 2017). ...
... Sen et al. (2011) state that Se and vitamin E supplementation increase the concentration of estrogen in preovulatory follicles, which has a positive effect on ovulation and pregnancy rates. As a result of the low levels of vitamin E in the dry pastures and stubbles, Koyuncu and Yerlikaya (2007) note that the risk of deficiency is considerable in sheep grazing in this area. From June through December, sheep's main feed sources are dry pastures and grain stubble. ...
... The pregnancy rate of the control group was found to be lower than the rate stated by Gordon (1997). Although there was no statistical difference between the groups, it was thought that giving stubble to sheep might have adversely affected fertility in the sheep in this study, given that it causes vitamin E deficiency (Koyuncu and Yerlikaya, 2007;White and Rewell, 2007;Liu et al., 2014). Awawdeh et al. (2019) reported that conception rates in the Awassi sheep during the transition period were 63.9% in the control group and 86.8% in the group that received vitamin E and Se injections after sponge insertion, removal, and on the 19th day after sponge removal. ...
The purpose of this study was to determine the effects of selenium, vitamin E, vitamin A, and vitamin D3 treatments on reproductive parameters in Awassi sheep fed solely dry grass and grain stubble during the breeding season with estrus synchronization. Seventy-five sheep were implanted with intravaginal sponges containing 20 mg of flugestone acetate for 9 days for estrus synchronization. On the day the sponges were inserted, the first group received an intramuscular injection of a supplement containing 200,000 IU of vitamin A, 30,000 IU of vitamin D3, and 20 mg of vitamin E, as well as a supplement containing 1 mg of sodium selenite and 60 mg of vitamin E. The second group was the control group, with no supplementary vitamin injected. On the day of sponge removal, the sheep received intramuscular injections of 500 IU PMSG and 250 mcg cloprostenol sodium in both groups. The sheep in the first group were given a second injection of the supplement on the same day that contained 20 mg of vitamin E, 30,000 IU of vitamin D3, and 200,000 IU of vitamin A. The sheep that showed signs of estrus were mated naturally after the estrus synchronization. Estrus rates were 86.11% and 85.29%, conception rates were 74.19% and 58.62%, pregnancy rates were 63.88% and 50%, lambing rates were 100% and 100%, and litter size was found to be 126.08% and 123.52% in Group I and II, respectively (P=0.858). Although there was no significant difference in the reproductive characteristics between the groups (P>0.05), Group I had a greater pregnancy rate and litter size. During the breeding season, it is believed that the regular application of vitamin and mineral supplements on a program basis in sheep fed only dry pasture and grain stubble contributed to fertility.
... Supplementation of ewes with Se and I before mating can increase fecundity by decreasing perinatal mortality and increasing lambing percentage (Grace and Knowles 2012). Koyuncu and Yerlikaya (2007) reported that Se (1.31) and Se + Vit E (1.48) supplementation significantly increased the fecundity rate compared to the control group (1.15). Although vitamin E and Se supplementation in Awassi ewes did not cause a statistical difference in fecundity, it was reported to be higher than that in the control group (Awawdeh et al. 2019). ...
The objective of this study was to evaluate the out-of-season reproductive performance and lamb birth weight of Kangal ewes orally administered a bolus of vitamin and mineral premix or injected with a mineral premix at 40 days postpartum during the anestrous period. In total, 78 primiparous Kangal ewes with were randomly allocated to three experimental groups. Estrus induction protocol was performed and a ram was introduced to the ewes at the 80th days postpartum. Ewes in the group 1 a dose of 2 mL of injectable mineral solution at 40-45 days before oestrous synchronisation, was administered at once (n = 25). As for group 2, at 40-45 days before oestrous synchronisation, a mineral bolus was given orally once (n = 27). To the ewes in the group 3 a dose of 2 mL of physiological saline was given once to the animals (n = 26) simultaneously with group 1 and group 2. Reproductive parameters such as estrus and pregnancy rates; single, twin, triplet, and multiple pregnancy rates; litter size; embryonic mortality; fecundity; and dystocia rates were evaluated. In addition, the placentas were weighed to evaluate the effect of mineral supplements on placentation. There were no significant differences between the groups in terms of parameters above (P > 0.05). However, the rate of dystocia was significantly lower in group 2 compared to Groups 1 and 3 (P < 0.05). In conclusion, As a result, it was determined that slow-releasing boluses could not produce efficacy during the throughout pregnancy.
... Also, N-SeG and SeG administration significantly (p < 0.05) induced a higher oestrus response and fertility rate, and the ewes treated with nano and organic Se came in oestrus earlier and remained longer than CG (p < .05). These findings are comparable to those of Koyuncu and Yerlikaya (2007) and Musa et al. (2018), who found that administering Se to Merino sheep improved oestrous response and fertility. Se is a cofactor in the glutathione peroxidase enzyme system responsible for detoxifying extracellular free radicals (Smith and Akinbamijo 2000). ...
... The conception rate was 56 vs. 68%, the lambing rate was 60 vs. 76%, and prolificacy was 1.07 vs. 1.12 (S anchez et al. 2008). Also, administration of Se by intramuscular injection has considerable favourable effects on the incidence of oestrus, fertility, and prolificacy in ewes, as well as the live weight increases of lambs up to 60 d of age (Koyuncu and Yerlikaya 2007). After two Se injections, Gabryszuk and Klewiec (2002) found that 3-year-old ewes had increased fertility, prolificacy, and body weight before mating and at lambing. ...
This study aimed to investigate the effects of nano and organic selenium on ovarian activity, fertility rate, and progesterone hormone levels in Ossimi ewes. Thirty ewes were treated with intra-vaginal sponges impregnated with medroxyprogesterone acetate (40 mg) for 14 days and simultaneously assigned randomly to three groups. The 1st group ewe served as control (CG). Ewes in the 2nd and 3rd groups were treated orally with organic selenium 3 mg/ewe and Nano-selenium 0.2 mg/ewes during intra-vaginal sponges (IVS) treatment SeG and N-SeG, respectively. The ovarian activity was monitored using an ultrasonic device, and serum samples were harvested for progesterone measurement. The results revealed that ewes in SeG and N-SeG groups had a significantly (P<0.05) higher number of small and large follicles after 48 hours of IVS withdrawal than in the CG, respectively, on the left ovary. Also, the N-SeG group had a larger diameter of the Corpus luteum on both ovaries' sides than CG, respectively, at the same time. However, the diameter of large follicles on both ovaries was significantly (P<0.05) larger in the N-SeG after 72 hours of IVS withdrawal than in SeG and CG. The ewes in N-SeG and SeG came in estrus earlier (P<0.05) than those in CG, and the estrus durations were longer (P<0.05) than that recorded in ewes of CG. The estrus response and fertility rate were higher (P<0.01) in N-SeG and SeG than in CG.
... To date, numerous studies have been conducted on the effects of nutrition on fertility, and it has been proven that feeding extra nutrients before and after mating increases both oocyte/embryo quality and superovulation (Kakar et al. 2005). Multiple studies have demonstrated that dietary supplementation with vitamins and trace minerals increases fertility (Ataman et al. 2020, Koyuncu and Yerlikaya 2007, Köse et al. 2013, Liu et al. 2014, Makkawi et al. 2009, Meza-Herrera et al. 2013, Yazlik et al. 2020. Two major vitamin supplements are β-carotene and vitamin E. It is known that β-carotene, which is converted to vitamin A by β-carotenase, is not only a vitamin A precursor, but also an antioxidant that complements the antioxidant activity of vitamin E. The requirement of the body for vitamin A, which is scarce in nature, is supplied from β-carotene found in plants. ...
... Vitamin A and vitamin E show a synergistic effect on ROS trapping, and if the placental transport of vitamins A and E between the mother and fetus is at a sufficient level, these vitamins enable protection from the destructive effects of lipid peroxidation. It has been reported that two injections of Se alone or Se plus vitamin E before mating improved the prolificacy of Merino ewes with no effects on lamb weights at birth (Koyuncu and Yerlikaya 2007). Furthermore, three injections (performed 2 weeks before CIDR insertion and at the time of the insertion and removal of CIDR) have been indicated to improve fertility, prolificacy, the lambing rate, and lamb viability, and reduce pregnancy losses (Farahavar et al. 2020). ...
This study was aimed at investigating the effects of vitamin A (VITA), vitamin E (VITE), and combined β-carotene plus vitamin E (βCAR+VITE) injections on some fertility parameters in ewes. Estrus synchronization was performed by treating the ewes with intravaginal FGA sponges impregnated with 30 mg of fluorogestone acetate. On the days of the insertion and withdrawal of the intravaginal sponges, groups VITA, VITE, and βCAR+VITE were administered with 500 000 IU of vitamin A, 50 mg of vitamin E, and a combination of β-carotene plus vitamin E, respectively. The ewes in the control group (C) were maintained for control purposes. Statistically significant differences were determined between groups VITA and βCAR+VITE, groups VITE and βCAR+VITE, and groups C and βCAR+VITE, as well as groups VITE and C, groups VITA and C for the multiple birth rates. While significant differences were determined between groups VITA and C, groups VITE and C, and groups βCAR+VITE and C for the lambing rates, it was ascertained that the ratio of newborn lambs to delivered ewes (litter size) significantly differed between groups VITA and βCAR+VITE, groups VITA and C, groups VITE and βCAR+VITE, groups VITE and C, and groups βCAR+VITE and C. The highest MDA level and lowest GSH level were determined on day 20 after mating in the control group. In conclusion, it is suggested that both multiple birth rates and litter size can be increased by the combined administration of β-carotene and vitamin E.
... According to Liu et al. (2014), dry grass pastures in the Mediterranean region have insufficient vitamin E content, particularly during the summer and autumn. According to Koyuncu and Yerlikaya (2007), sheep fed grass on dry pastures and stubbles with low vitamin E levels are at a particularly high risk of deficiency. We found no statistically significant differences in fertility parameters between the groups in our study, which may be related to the geographic layout and climatic features of the study area. ...
... Injections of vitamin E and Se during the breeding season enhanced estrous and pregnancy rates, offspring yields, and improved reproductive metrics in Merino sheep, according to a study by Koyuncu and Yerlikaya (2007). During the mating season, El-Shahat and Abdel Monem (2011) added various amounts of vitamin E and Se to the feed of Baladi sheep and saw a higher pregnancy rate in the experimental groups compared to the controls. ...
... During the mating season, El-Shahat and Abdel Monem (2011) added various amounts of vitamin E and Se to the feed of Baladi sheep and saw a higher pregnancy rate in the experimental groups compared to the controls. There are studies that show supplementation with vitamin E and Se improves sheep fertility (Koyuncu and Yerlikaya, 2007; El-Shahat and Abdel Monem, injected Mehraban sheep with 5 ml Ese (0.5 mg/ml sodium selenite and 50 IU DI-α-tocopherol) 2 weeks before CIDR insertion, during CIDR insertion, and during CIDR removal at synchronization during the breeding season. CIDR stayed for 13 days, and the authors discovered no differences in estrous, pregnancy, or twin births between the groups. ...
The aim of this study was to evaluate the effect of selenium, β-carotene, and vitamin E administration on fertility of Awassi ewes synchronized in non-breeding season. A total of 80 multiparous Awassi ewes, aged 2 to 6 years were enrolled in the study. Intravaginal sponges containing flugeston acetate (20 mg cronolon) was inserted into vagina and allowed to remain in vagina for nine days. Ewes were randomly divided into two groups. Group I received intramuscular injections of 1 mg sodium selenite, 60 mg vitamin E, 75 mg β-carotene, and 100 mg DL-α-tocopherol acetate at sponge insertion, sponge removal, and 18 days after the introduction of ram. Group II remained as control group and received no treatment. On the removal of the sponges, 500 IU eCG and 0.075 mg D-cloprostenol were injected intramuscularly. Ram was introduced for 1 hr twice a day 24 hours after the sponge removal. Interval between sponge removal and estrus, estrus rates, conception rates, pregnancy rates, lambing rates, and fecundity rates in group I and group II were 45.30±1.71 and 43.94±1.72 hours, 79.1% and 86.6%, 66.66% and 72.41%, 54.05% and 58.33%, 100% and 100%, and 135% and 138%, respectively. There were no statistical differences between the groups (p>0.05). In conclusion, the administration of Se, β-carotene, and vitamin E in estrus synchronization protocols in non-breeding season had no positive effect on the fertility characteristics of Awassi sheep.
... Tilgner (1999) and Shams El-Din et al. (2018) both found that increasing of feed intake which leads to improve daily weight gain and final weight of lambs. On the other hand, the presence of vitamin E in the third treatment may have played a key role activating a processes of nutrient absorption into body tissues, leading to an increase protein tissue deposition of animal's body, as evidenced by improvement in daily and total weight gain of lambs treated with vitamin E. (Abdi, 2006, Koyuncn andYerlikaya, 2007). Also, The combination of (ginger roots + vitamin E) by lambs that to improve animals appetite, leading to an increase of feed intake, which in turn leads to strengthening of protein tissues of body tissues which resulting a significant increase on final weight, total weight gain of Awassi lambs (Al-Rawi et al 2004). ...
To find out effects of adding ginger roots powder and vitamin E and mutual synergy between them on productive performance and some carcass features of Awassi lambs. An experimement was conducted at animal farm designated for raising sheep of the Department of Animal Production/College of Agriculture and Forestry, University of Mosul. Twenty-four of Awassi lambs (males) were selected homogeneously with average of initial weight (27.250- 27.525 kg) and close in age (5.5-6 months) at the beginning of experiment. The fattening diet was prepared as a peleted ration free of feed additives (control diet).While ginger roots powder was added at a rate of 20 gm/kg dry matter to the second ration and vitamin E was added at a rate of 200 mg/kg to the third diet's components.As for fourth treatment a mixture of 20 gm of ginger roots powder and 200 mg of vitamin E was added to concentrate pelleted. The lovable concentrated diets of Awassi lambs were provided with uniform protein level (15.59%) and metabolize energy level (2750 Kcal) during fattening period (90 day). The current study found that lambs treated with the experimental treatments had significantly higher rates of final weight, daily gains, and total weight than lambs treated with the control treatments. The rates of final weight were 45.475, 48.167, 49.410, 51.512 kg, daily weight gain was 199, 232, 244, 268 gm/day and total weight gain was 17.983, 20.917, 21.978, 24,205 kg/head for four treatments respectively. In terms of carcass features, the results demonstrated a highly significant improvement (P≤0.01) on an averages of hot and cold carcasses weights was in favor of lambs treated with ginger, vitamin E, and a synergistic treatment between them as compared to lambs given with a control treatment. The averages of hot carcass weights were 20.983, 24.545, 25,711, 27.580 kg, and cold carcass weights were 20.515, 24.177, 25.325, 26,994 kg for four treatments respectively.While the current study found a substantial superiority (P≤0.05) on rates of ocular muscle area and significant decrease on fat under skin thickness which was comparison to the control group.
... Trace minerals such as copper (Garcia-Diaz et al., 2012;Roychoudhury et al., 2014;Soni et al., 2018) and selenium (Basini and Tamanani et al., 2000;Gabryszuk et al., 2002;Koyuncu and Yerlikaya 2007;Yao et al., 2018) were largely found to regulate ovarian granulosa cell estradiol synthesis and estrus behaviour in ruminants. Copper supplementation in vivo significantly increased estradiol, progesterone, FSH and LH concentration in Simmental heifers (Wang et al., 2008). ...
... Copper supplementation in vivo significantly increased estradiol, progesterone, FSH and LH concentration in Simmental heifers (Wang et al., 2008). Similarly, selenium supplementation in vivo significantly increased follicular growth (Vázquez-Hernández et al., 2017), estrus response (Gabryszuk et al., 2002;Koyuncu and Yerlikaya 2007;Wani et al., 2016) and conception rate (Ganie et al., 2014;Musa et al., 2018) in ruminants. The existing evidences are based on prolonged dietary supplementation and/or multiple parenteral administrations of copper and selenium, while studies are meager on single parenteral administration of copper and selenium in combination with PGF 2 α during estrus synchronization protocols. ...
Background: Copper and selenium were proven modulaters of reproductive function in ruminants under dietary supplementation. Their effects under pareneral administraton during estrus synchronization are not clearly defined. On this background the present was aimed to evaluate the effect of copper and selenium on estrus associated responses in goats. Methods: Thirty adult female Salem black goats were selected. On day ten of the estrus cycle, 250 µg of cloprostenol injection was given intramuscularly to all the animals and assigned to five groups. GI: control, GII: 4 µg of Buserelin, GIII: 20 mg cupric chloride, GIV: 10 mg sodium selenite and GV: copper plus selenium injections were administrated. Whole blood was collected for seven days for hormone assay. Estrus was detected using aproned bucks. Result: There was no significant (p>0.05) difference in estrus response, onset and duration of estrus between groups. The progesterone concentration decreased significantly (p<0.05) from day 0 (before PGF 2 α) to day 1 (after PGF 2 α) in all groups. There was a significant (p<0.05) increase in estradiol and progesterone concentration in the GnRH group compared to other groups. Parenteral administration of copper and selenium did not significantly improve estrus behavior, estradiol and progesterone concentration in Salem black goats. GnRH was once again proved to be effective in the improvement of estrus associated responses in goats.
