Figure - available from: Archives of Toxicology
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Seizure behavior is mitigated by subunit-selective PAMs. A Schematic of the experimental paradigm. B Seizure counts in larvae exposed to subunit-selective PAMs after 3.5-h exposure to 300 µM RDX. Individual dots represent individual larvae. Bars are mean ± 95% CI. *p < 0.05 in comparison to DMSO-only, ^p < 0.05 in comparison to 3 µM MDZ, #p < 0.05 in comparison to RDX-only (0 µM) as determined using Dunnett’s multiple t test (n = 47–48 larvae from at least three individual spawns)
Source publication
Hexahydro-1,3,5-trinitro-1,3,5-triazine, or Royal Demolition Explosive (RDX), is a major component of plastic explosives such as C-4. Acute exposures from intentional or accidental ingestion are a documented clinical concern, especially among young male U.S. service members in the armed forces. When ingested in large enough quantity, RDX causes ton...
