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Schematics demonstrating the original Beer-Lambert Law and Modified BeerLambert Law. Where (A) for a non-scattering solution and the subsequent MBLL (B) to account for scattering in biological tissues. A, absorption; [C] concentration of compound of

Schematics demonstrating the original Beer-Lambert Law and Modified BeerLambert Law. Where (A) for a non-scattering solution and the subsequent MBLL (B) to account for scattering in biological tissues. A, absorption; [C] concentration of compound of

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Sufficient tissue perfusion and oxygenation are vital for all metabolic processes in cells. When tissue perfusion is unable to meet the metabolic demands of the tissue, inadequate supply of oxygen may occur, leading to tissue hypoxia. It is the role of various regulatory mechanisms in the cardiovascular and respiratory systems to ensure proper oxyg...

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... is not possible, as light does not move through tissue uniformly but instead is affected by scattering and absorption; an example of this is shown in Figure 2. Consequently, the Modified Beer Lambert Law (MBLL) is used to calculate the concentration of oxygenated haemoglobin (O2HB) and deoxygenated haemoglobin (HHB) in tissue. ...