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Background:
Endoscopic submucosal dissection (ESD) of esophageal superficial neoplasm is associated with a high en bloc R0 resection rate and low recurrence.
Objective:
We aim to compare the performance and clinical outcomes of ESD via ESD after circumferential incision (ESD-C) versus submucosal tunneling (ESD-T).
Methods:
Single-center retros...
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Background and purpose
Endoscopic submucosal dissection (ESD) is a promising technique for superficial esophageal lesions. However, stricture is a frequent adverse complication. This study was performed to develop a precise and convenient score prediction model for esophageal strictures after ESD, and compare its efficacy with a previously publishe...
Citations
... However, it is encouraging that on-demand dilation had a good therapeutic effect for these patients, with 92.65% achieving long-term relief of the stricture after a median of 5 endoscopic dilation sessions, consistent with similar research conclusions [19,20]. The recurrence rate after ESD for superficial esophageal cancer ranges from 2.4% to 11.6% [21,22]. In our study, the recurrence rate was 4.62%, with two cases of in situ recurrence and one case of lymph node recurrence. ...
Objective
This study aims to investigate the efficacy and safety of snare traction-assisted endoscopic submucosal dissection (ESD) for the management of circumferential superficial esophageal cancer.
Methods
A total of 68 patients who underwent ESD for circumferential superficial esophageal cancer were included in this study. All the patients were divided into two groups based on whether the snare traction was used or not; the snare traction group (S-ESD, group n = 35) and the control group (C-ESD, group n = 33).
Results
There was no significant difference in the size of the resected area between the groups [21.98 (18.30, 27.00) cm² vs 24.00 (15.28, 30.72) cm², P = 0.976]. The snare traction group had a shorter dissection time [92.00 (74.00, 121.00) min vs 110.00 (92.50, 137.00) min, P = 0.017] and a faster resection speed [0.28 ± 0.13 cm²/min vs 0.22 ± 0.11cm²/min, P = 0.040] compared to the control group. There were no statistically significant differences between the two groups in terms of hospital stay, cost, en bloc resection rate, R0 resection rate, curative resection rate, bleeding rate, perforation rate, stricture rate, and recurrence rate (P > 0.05).
Conclusion
Snare traction-assisted ESD is a safe and efficient approach for the treatment of circumferential superficial esophageal cancer. Its advantages includes shorter procedure so the anesthesia requirement, clear operative filed view, improved mucosal dissection efficiency, simple, and easily accessible equipment.
Graphical abstract
... The expansion of ESD in the Latin America is crucial to increase the en bloc resection rate of esophageal tumors regardless of their size, allowing precise histological assessment and reliable staging. [17][18][19][20][21][22][23][24][25][26][27][28][29] The aim of our research was to present the results of a large series of patients with early esophageal neoplasms managed by ESD by a single trained operator and to compare the clinical outcomes of the patients with those obtained at Japanese endoscopic centers. ...
Background/aims:
Endoscopic submucosal dissection (ESD) is currently considered the first-line treatment for the eradication of superficial neoplasms of the esophagus in Eastern countries. However, in the West, particularly in Latin America, the experience with esophageal ESD is still limited because of the high technical complexity required for its execution. This study aimed to present the results of the clinical application of ESD to manage superficial esophageal neoplasms in a Latin American center in over 100 consecutive cases.
Methods:
This retrospective study included consecutive patients who underwent endoscopic ESD for superficial esophageal neoplasms between 2009 and 2022. The following clinical outcomes were assessed: en bloc, complete, and curative resection rates, local recurrence, adverse events, and procedure-related mortality.
Results:
Esophageal ESD was performed mainly for squamous cell carcinoma (66.6%), high-grade intraepithelial neoplasia (17.1%), and adenocarcinoma (11.4%). En bloc and complete resection rates were 96.2% and 81.0%, respectively. The curative resection rate was 64.8%. Adverse events occurred in six cases (5.7%). Endoscopic follow-up was performed for an average period of 29.7 months.
Conclusions:
ESD performed by trained operators is feasible, safe, and clinically effective for managing superficial neoplastic lesions of the esophagus in Latin America.
... Also scopic submucosal dissection with circumferential incision (ESD-C) versus tunneling method for treatment (ESD-T) of superficial esophageal cancer (9) . The first technique is performed through an incision along the oral margins and next at the caudal margin of the lesion, resulting in a C-shaped incision. ...
