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Schematic presentation of correspondences between human chromosomes and SSC1q IMpRH maps. (a) The correspondences of human chromosomes (Build 33) to SSC1q in Meyers et al. (2005), who reported seven conserved regions of synteny between SSC1q and the human chromosomes. (b) The correspondences of human chromosomes (Build 36.2) to SSC1q in our study.
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A large number of significant QTL for economically important traits including average daily gain have been located on SSC1q, which, as shown by chromosome painting, corresponds to four human chromosomes (HSA9, 14, 15 and 18). To provide a comprehensive comparative map for efficient selection of candidate genes, 81 and 34 genes localized on HSA9 and...
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A high-resolution comprehensive map was constructed for porcine chromosome (SSC) 6, where quantitative trait loci (QTL) for reproduction and meat quality traits have been reported to exist. A radiation hybrid (RH) map containing 105 gene-based markers and 15 microsatellite markers was constructed for this chromosome using a 3000-rad porcine/hamster...
Citations
... From the analysis of 1150 pig-genome transcripts which were generated in our previous study (Park et al., 2009) The annotation of sequences for pig transcripts with an asterisk (*) were carried out in this study since either only unannotated sequences or sequences from species other than pig were available in the public database. mapped markers (Farber et al., 2003;Jiang et al., 2003;Cao et al., 2004;Caetano et al., 2005;Cepica et al., 2005;Leeb et al., 2005;Wang et al., 2005;Shimogiri et al., 2006;Yasue et al., 2008;Liu et al., 2008;Ma et al., 2009), designed primers for RH mapping, and performed PCR against the SSRH radiation hybrid cell panel. Among them, 38 pairs of primers showed pig-specific amplification and were used for RH mapping. ...
We performed RH mapping of 38 transcripts including 7 previously mapped markers selected from full-length enriched cDNA libraries
of pigs to determine their locations within the porcine genome and mapped them to 13 chromosomes. The chromosomes with the
largest number of mapped transcripts were Sus scrofa chromosome (SSC) 1 with 6, and 5 transcripts were mapped to SSC6 and
9 each. The average retention frequency of the amplified products was 31%, ranging from 74% for SSC9 to 12% for SSC17. The
evolutionary conservation of syntenic structures for the chromosomal regions linked to the 38 genes was confirmed using 86
previously mapped genes surrounding them, indicating that the general syntenic structures of chromosomes were conserved among
cattle, humans and pigs except for the presence of additional chromosomal breakages in humans and bovine due to an increase
in chromosome numbers. The mapping information of 31 new genes can be used to more finely analyze the pig genome or could
be used as functional gene markers for porcine QTL mapping.
KeywordsRadiation hybrid map-Sus scrofa chromosome-Comparative map-Full-length cDNA library-Korean native pigs
The second edition of this book contains chapters that discuss modern pig genetics, including taxonomy and evolution, domestication, coat colour variation, morphological traits and hereditary diseases, immunogenetics, cytogenetics, genomics, behaviour genetics, reproduction, transgenics, developmental genetics, pig genetic resources, performance traits, carcass and meat quality genetics, genetic improvement, pigs as models for biomedical sciences, pig breeds and genetic nomenclature. This book is intended for those who study or work with pigs.
To provide a gene-based comparative map and to examine a porcine genome assembly using bacterial artificial chromosome-based sequence, we have attempted to assign 128 genes localized on human chromosome 14q (HSA14q) to a porcine 7000-rad radiation hybrid (IMpRH) map. This study, together with earlier studies, has demonstrated the following. (i) 126 genes were incorporated into two SSC7 RH linkage groups by CarthaGene analysis. (ii) In the remaining two genes, TOX4 linked to TCRA located in SSC7 by two-point analysis, whereas SIP1 showed no significant linkage with any gene/marker registered in the IMpRH Web Server. (iii) In the two groups, the gene clusters located from 19.9 to 36.5 Mb on HSA14q11.2-q13.3 and from 64.0 to 104.3 Mb on HSA14q23-q32.33 respectively were assigned to SSC7q21-q26. (iv) Comparison of the gene order between the present RH map and the latest porcine sequence assembly revealed some inconsistencies, and a redundant arrangement of 16 genes in the sequence assembly.
