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Schematic diagram showing application of various 2D TMD materials in biosensing. Clockwise: in order of increasing complexity of molecules, starting from ROS (reactive oxygen species) to CEA (carcioembrionic antigen).
Source publication
The interest in two-dimensional and layered materials continues to expand, driven by the compelling properties of individual atomic layers that can be stacked and/or twisted into synthetic heterostructures. The plethora of electronic properties as well as the emergence of many different quasiparticles, including plasmons, polaritons, trions and exc...
Contexts in source publication
Context 1
... high surface-to-volume ratio offers potential for the detection of large amounts of target analytes and low power consumptions. The current state of growth is such that 2D TMDs can be readily synthesized on a large scale and can be directly dispersed in aqueous solution without the aid of surfactants, providing environmentally friendly and even biocompatible and biodegradable solutions [174,[222][223][224]. Figure 12 schematically summarizes the broad range of applications of 2D TMD biosensors for the detection of various molecules. Specifically owing to its high conductivity and a large number of active defects that provide sites for adsorption of biomolecules, MoS2 is one of the most commonly used TMD materials for biosensing [174]. ...
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... owing to its high conductivity and a large number of active defects that provide sites for adsorption of biomolecules, MoS2 is one of the most commonly used TMD materials for biosensing [174]. Either in its pristine form or as a part of hybrid structures/nanocomposites, MoS2 has been used both as a platform for non-enzymatic sensing and as a biocompatible matrix for enzyme immobilization and development of both electrochemical sensors and biosensors [ Figure 12 and Figure 13(a)] [217,225,226]. detection range (bottom) for glucose detection using graphene, GO, rGO and MoS2 sensors. ...
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... values are summarized based on the results presented in this review and [174] MoS2-based FETs have been successfully employed as a 2D platform for detections of various biomolecules, including streptavidin and biotin [228], ochratoxin [229][230][231], dopamine [232], anti-PSA [233,234], TNF-α [235,236], or bisphenol A [222]. We will further discuss these applications in order of increasing weight and complexity of biomolecules [ Figure 12]. Specifically, for streptavidin and biotin detection (one of the strongest known binding reactions in biology), it has been demonstrated that MoS 2 -based sensors provide specific protein sensing at concentrations as low as 100 fM. ...
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