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Salmonella typhi sepsis . Typhoid nodule (center) composed oflymphocytes and hyperplastic Kupffer cells distends a sinusoid. The edge of a portal area is at lower right. (H&E, x 300; AFIP Neg. 87-5870)  

Salmonella typhi sepsis . Typhoid nodule (center) composed oflymphocytes and hyperplastic Kupffer cells distends a sinusoid. The edge of a portal area is at lower right. (H&E, x 300; AFIP Neg. 87-5870)  

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A variety of infectious diseases may produce jaundice or other biochemical abnormalities, even though the liver is not the primary site of infection.1–3 Despite the often serious nature of the infection or underlying disease process, the hepatic aspects are generally not life-threatening. However, the assorted liver aspects can mimic extrahepatic o...

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Bile is a solution of organic and inorganic compounds in water. It is produced by hepatocytes and secreted into the bile canaliculi (canalicular bile). It is then modified as it passes through intrahepatic bile ductules and ducts (ductular bile). Most of the bile entering the extrahepatic biliary tree enters the gallbladder, where it is concentrated and stored between periods of digestion (gallbladder bile). Finally, meals stimulate gallbladder emptying which projects bile through the common bile duct into the duodenum, where bile facilitates digestion.