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SPORADIC CASES OF BORNHOLM DISEASE, BY AGE,

SPORADIC CASES OF BORNHOLM DISEASE, BY AGE,

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Bornholm disease is generally attributed to infection with Coxsackie viruses of the B group, but in 1954-56 a number of sporadic cases occurred in Bytom, Upper Silesia, which were shown on virological examination to be caused by Coxsackie A4. In 1957, however, in the same area, an epidemic of Bornholm disease broke out for which Coxsackie B virus w...

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... gaps in the world picture of the geographical and time distribution of Bornholm disease. SPORADIC CASES, 1954-56 From 1954to 1956e., at a time when only sporadic cases appeared, 37 out of 64 clinically diagnosed cases were examined virologically. An age study of 62 of these cases showed that the majority occurred in the age-group 20-40 years ( Fig. 1). Children under 14 were not included in our studies. Fig. 2 represents the incidence of the disease in various months. As is typical with this disease, the greatest incidence was seen in late summer and at the beginning of autumn, while in May and June no cases ...

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BORNHOLM disease, or pleurodynia, is generally associated with Group B Coxsackie viruses.1 This group of viruses is also responsible for such diverse clinical syndromes as meningitis, encephalitis and myocarditis. Although Coxsackie viruses Group A, Types 4 and 6, have been isolated from patients with pleurodynia,2 , 3 Group B viruses have thus far been the agents most commonly associated with this syndrome.1 , 4 , 5 Certain members of the enterovirus family, the ECHO viruses, are still in search of disease.6 ECHO virus Type 8 is an example, with no heretofore proved association with human disease. The present report describes a clinical case of pleurodynia, which . . .