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Role of excimer laser coronary atherectomy in acute myocardial infarction setting was studied in two large studies -CARMEL and Laser acute myocardial infarction study
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In the present era, percutaneous coronary intervention is being done for various types of coronary lesions worldwide. However, calcified and fibrotic lesions have remained a major challenge in coronary interventions. Conventionally, cutting balloon and rotational atherectomy have been being used in calcified and fibrotic lesions. Excimer laser coro...
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This study aimed to evaluate the efficacy and safety of excimer laser coronary atherectomy (ELCA) prior to paclitaxel-coated balloon angioplasty for de novo coronary artery lesions. This retrospective observational study analyzed 118 eligible patients with de novo coronary artery disease whose only percutaneous coronary intervention was a drug-coat...
Citations
... The penetration depth of excimer lasers is shallow, which ensures accurate ablation of tissue without generating too much heat and minimizes inadvertent tissue damage. Excimer laser angioplasty is mediated by three different mechanisms: photochemical, photothermal, and photomechanical [114]. Photochemical action does not generate heat and excimer laser energy is larger than the binding energy of molecular bonds, which leads to the fracture of molecular mechanical bonds. ...
Blood vessels are one of the most essential organs, which nourish all tissues in our body. Once there are intravascular plaques or vascular occlusion, other organs and circulatory systems will not work properly. Therefore, it is necessary to detect abnormal blood vessels by intravascular imaging technologies for subsequent vascular treatment. The emergence of lasers and fiber optics promotes the development of intravascular imaging and treatment. Laser imaging techniques can obtain deep vascular images owing to light scattering and absorption properties. Moreover, photothermal and photomechanical effects of laser make it possible to treat vascular diseases accurately. In this review, we present the research progress and applications of laser techniques in intravascular imaging and treatment. Firstly, we introduce intravascular optical coherent tomography and intravascular photoacoustic imaging, which can obtain various information of plaques. Multimodal intravascular imaging techniques provide more information about intravascular plaques, which have an essential influence on intravascular imaging. Secondly, two laser techniques including laser angioplasty and endovenous laser ablation are discussed for the treatment of arterial and venous diseases, respectively. Finally, the outlook of laser techniques in blood vessels, as well as the integration of laser imaging and treatment are prospected in the section of discussions.
