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Introduction:
As surgical site infections (SSIs) after joint arthroplasty contribute to increased morbidity and mortality, they require further surgical intervention, prolonged hospitalisation, and antimicrobial treatment. The aim of our study is to examine the association between preoperative quality of life (QoL) and other predictive factors on...
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Context 1
... to the demographics in Table 5, patients aged ≥65 years received antibiotic treatment for SSI at a statistically signiicant lower rate of 87% (odds ratio: 0.13, 95% CI:0.03-0.62) compared to younger patients. ...Context 2
... patients aged ≤65 treated with THR or TKR appeared at higher risk (55.6%) for SSI compared to elderly individuals (15.8%), which was not related to demographic or surgical characteristics (chisquare test: p � 0.002). Moreover, the relationship between other factors under investigation and SSIs is depicted in Table 5. ...Citations
... [1] TKA aims to improve the quality of life of individuals with end-stage osteoarthritis by reducing pain and increasing function, and was found to improve patients' sports and physical activity. [2,3] Total hip arthroplasty (THA) is one of the most cost-effective and consistently successful surgeries performed in orthopaedics. [2] It provides reliable outcomes for patients suffering from endstage degenerative hip osteoarthritis. ...
... [2,3] Total hip arthroplasty (THA) is one of the most cost-effective and consistently successful surgeries performed in orthopaedics. [2] It provides reliable outcomes for patients suffering from endstage degenerative hip osteoarthritis. Specifically, it results in pain relief, functional restoration, and improved quality of life. ...
... [5] Total knee arthroplasty is more commonly performed on women and individuals of older ages. Dramatic increases in TKA surgeries are projected to occur with an increasing rate of younger TKA recipients under the age of 60. [2] However according to Hawker et al, younger people undergoing TKA for knee osteoarthritis are more likely to have morbid obesity, they smoke, and their expected outcome is to return to vigorous activities, like sport. [6], Approximately 28% of the population ≥45-year-old suffer from hip arthritis and this prevalence is expected to increase in coming decades. ...
This study focuses on the evaluation of antibiotic therapy in preoperative and postoperative conditions of Total Knee Arthroplasty (TKA) or Total Hip Arthroplasty (THR) in patients with osteoarthritis. The analysis of data from the study reveals that osteoarthritis predominantly affects individuals above 45 years, with an increased incidence after the age of 55. Females represent 64.3% of diagnosed patients, indicating a higher predisposition in women. Primary complaints include knee and hip pain, difficulty in walking, stiffness, and swelling, with walking difficulty and stiffness being prominent. Patients with osteoarthritis commonly exhibit comorbidities, with hypertension and diabetes being prevalent, alongside other conditions such as heart, thyroid, and kidney-related disorders. Among osteoarthritis patients, 71.4% required Total Knee Replacement (TKR), while 28.6% required Total Hip Replacement (THR). Female patients comprised a higher percentage for both TKR (65%) and THR (62.5%). Antibiotic administration pre-surgery primarily involved Inj. Cefuroxime (1.5gm) or Inj. Amikacin (500mg), with 37.5% receiving both. Similarly, during surgery, 64.3% of patients received both antibiotics. Post-surgery antibiotic regimens mirrored the pre-surgery administration. This data provides valuable insights into the demographic distribution, comorbidities, surgical requirements, and antibiotic usage patterns in osteoarthritis patients undergoing TKR and THR surgeries. The findings contribute to a comprehensive understanding for future research and clinical interventions, aiming to enhance patient care and optimize treatment strategies in orthopedic procedures.
... In the EU, ferric carboxymaltose administration is advised when oral iron preparations are ineffective or contraindicated. Common adverse drug reactions observed during clinical studies or reported in post-marketing experiences include nausea (the most frequent reaction), injection site reactions, hypophosphataemia, headache, flushing, dizziness, fever, and hypertension [29][30][31]. ...
Total hip arthroplasties aim to improve quality of life and reduce pain in patients suffering from late-stage hip osteoarthritis. On the other hand, it may represent a risky surgical procedure in people who refuse blood products because of religious beliefs, such as Jehovah’s Witnesses (JW). Preoperative optimisation protocols of these patients allow medical professionals to perform arthroplasties in a safer manner, avoiding allogeneic blood transfusion. In our retrospective study, two groups of patients were evaluated. Group 1 included JW patients who underwent a preoperative Hb optimisation program; Group 2 included non-JW patients authorizing transfusion in case of necessity. Differences in Hb levels were as follows: before surgery (JW 14.24 ± 1.10 vs. non-JW 12.48 ± 1.00, p-value ≤ 0.05), and after surgery (day 1 Hb: JW 12.88 ± 0.90 vs. non-JW 10.04 ± 1.30, p-value ≤ 0.05; day 3 Hb: JW 14.65 ± 0.80 vs. non-JW 9.10 ± 0.90 p-value ≤ 0.05). Moreover, cost-effectiveness strategies were evaluated in both groups. Our findings support that patient blood management programs are a safe and good strategy in hip prosthetic surgery, decreasing risks and transfusion overuse.
