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Results of deterministic sensitivity analysis. DTX, docetaxel; FN, febrile neutropenia; ICER, incremental cost-effectiveness ratio; Peg-G, pegfilgrastim; QALY, quality-adjusted life year; RAM, ramucirumab; WTP, willingness to pay. The vertical axis represents the base-case ICER, horizontal bars represent the difference between the base-case ICER and ICER generated when the model was run using the high and low values of the plausible range, and the entire length of each horizontal bar represents the magnitude of variation in the cost-effectiveness results

Results of deterministic sensitivity analysis. DTX, docetaxel; FN, febrile neutropenia; ICER, incremental cost-effectiveness ratio; Peg-G, pegfilgrastim; QALY, quality-adjusted life year; RAM, ramucirumab; WTP, willingness to pay. The vertical axis represents the base-case ICER, horizontal bars represent the difference between the base-case ICER and ICER generated when the model was run using the high and low values of the plausible range, and the entire length of each horizontal bar represents the magnitude of variation in the cost-effectiveness results

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Purpose The dose-limiting factor of ramucirumab plus docetaxel (RAM + DTX) in patients with non-small cell lung cancer (NSCLC) is febrile neutropenia (FN), which has a high incidence in Asians. This study aimed to evaluate the cost-effectiveness of pegfilgrastim (Peg-G) in patients with NSCLC receiving RAM + DTX in Japan. Methods We simulated mode...

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