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Restricted cubic spines analysis of the association of FT3 levels and risk of CI-AKI. X-axis represents plasma FT3 concentrations. Y-axis represents the probability of CI-AKI. Dashed lines indicate 95% CI. From left to right, the triangles indicate the 20th, 40th, 60th, and 80th percentile.
Source publication
Objective
Post-treatment contrast induced acute kidney injury (CI-AKI) is associated with poor outcomes in patients with acute myocardial infarction (AMI). A lower free triiodothyronine (FT3) level predicts a poor prognosis of AMI patients. This study evaluated the effect of plasma FT3 level in predicting CI-AKI and short-term survival among AMI pa...
Context in source publication
Context 1
... 95% CI: 0.32-0.81 for quartile 4 vs quartile 1, P trend = 0.005). To be specific, the risk of CI-AKI decreased by 18.9% when FT3 level increased by one s.d. (95%CI: 0.69-0.95, P = 0.011) after multivariable adjustment. Restricted cubic splines showed a similar result. The OR declined dramatically as FT3 rose to 4 pmol/L, but then flattened out (Fig. ...
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... Early identification of patients at a high risk of various complications is important, and an artificial intelligence model for predicting acute kidney injury risk and a new scoring system for predicting ventricular arrhythmia risk have been developed [33,41]. In our previous studies, we have also found that a low level of free triiodothyronine is independently associated with the short-term outcomes in patients with AMI [42]. Prevention is important, but treatment is equally vital and SGLT2 inhibitors provide a new therapeutic direction for the prognosis of AMI patients. ...
Objective
The aim of this study was to investigate the effect of dapagliflozin (DAPA) on the rate of heart failure rehospitalization in patients with acute myocardial infarction (AMI) and type 2 diabetes mellitus (T2DM).
Methods
AMI patients with T2DM from CZ-AMI registry between January 2017 and January 2021 were enrolled in this study. Patients were stratified into DAPA users and non-DAPA users. The primary outcome was the incidence of heart failure rehospitalization. Kaplan–Meier analysis and Cox regressions were performed to evaluate the prognostic significance of DAPA. Propensity score matching (PSM) was performed to minimize the bias of confounding factors and facilitate the comparability between groups. The enrolled patients were matched with a propensity score of 1:1.
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Conclusion
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... 35 In our previous studies, we have also found that a lower systolic blood pressure level at admission and a low level of free triiodothyronine are independently associated with the short-term outcomes in patients with AMI. [36][37][38] In the current study, hypotension and free triiodothyronine were not associated with the risk of VA. Therefore, more attention should be paid to blood glucose and renal function in patients with AMI. ...
Objective:
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Methods:
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Results:
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Conclusion:
We have established a clinical prediction risk score for predicting the occurrence of VA in AMI patients. The prediction score is easy to use, performs well and can be used to guide clinical practice.
Objective
This study aimed to explore the association of preoperative neutrophil percentage (NEUT%) with the risk of acute kidney injury (AKI) in patients with acute myocardial infarction (AMI) having undergone coronary interventional therapy.
Methods
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Results
A total of 3001 consecutive patients were enrolled with an average age of 64.38 years. AKI occurred in 327 (10.9%) patients. The NEUT% was higher in the AKI group than in the non-AKI group ([76.65±11.43]% versus [73.22±11.83]%, P<0.001). NEUT% was also identified as an independent risk factor for AKI in AMI patients after adjustment (OR=1.021, 95% CI: 1.010–1.033, P < 0.001). Compared with those at the lowest quartile of NEUT%, the patients at quartiles 2–4 had a higher risk of AKI (P for trend = 0.003). The odds of AKI increased by 29.0% as NEUT% increased by 1 standard deviation (OR=1.290, 95% CI: 1.087–1.531, P = 0.004). After a median of 35 days follow-up, 93 patients died. Patients with a higher NEUT% presented a higher risk of all-cause death after AMI (Log rank: χ² =24.753, P<0.001).
Conclusion
In AMI patients, the peripheral blood NEUT% was positively associated with the odds of AKI and short-term all-cause mortality. NEUT% may provide physicians with more information about disease development and prognosis.
