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Understanding protein secretion pathways are of paramount importance in studying diseases caused by bacteria and their respective treatments. Most such paths must signal ways to identify secretion. However, some proteins, known as non-classical secreted proteins, do not have signaling ways. This study aims to classify such proteins from predictive...
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Context 1
... addition, the attributes of basicity and acidity are also essential in the secretion process. Together, these characteristics distinguish four groups of amino acids, as shown in Figure 1. ...
Context 2
... could argue that the number of elements used to train the models of this work would be responsible for this bias. However, we also obtained above-average results in predicting positives even with this bias for predicting negatives (tests 1 and 3), also an unexpected result considering the tendency due to the overrepresentation of a data class. On average, the specificity and sensitivity of our predictors were 89 and 62%, respectively. ...
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