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Relief after 2w-4w transnasal ileum tube insertion by X-ray. A image of X-RAY after transnasal ileum tube insertion of patient 1; B image of X-RAY after X-RAY of patient 2; C image of X-AY after transnasal ileum tube insertion of patient 3; D image of X-AY after transnasal ileum tube insertion of patient 4; E image of X-AY after transnasal ileum tube insertion of patient 5; F image of X-AY after transnasal ileum tube insertion of patient 6. B–F indicated fully relieved; A indicated partially relieved
Source publication
Background
Previous studies reported that transnasal ileus tube was a new and useful method for rapid relief of small intestinal obstruction. However, no study reported the impacts of the transnasal ileus tube for Crohn’s disease combined with intestinal obstruction. We aimed to describe the strategy to the small intestine obstruction caused by Cro...
Citations
... Meglumine diatrizoate has the characteristics of hypertonicity and has been shown to induce no apparent adverse reactions. After decompression through the intestinal obstruction catheter, angiography can significantly reduce the dilution of contrast medium by intestinal effusion and improve the effectiveness of diagnosis and treatment [3][4][5]. In addition to being used as a contrast agent, oral administration of meglumine diatrizoate can reduce intestinal wall edema, dilate the small intestine at the distal end of obstruction, stimulate gastrointestinal peristalsis, and relieve intestinal obstruction. ...
Background:
Early postoperative inflammatory small bowel obstruction (EPISBO) is easy to be complicated after colorectal cancer surgery. Both intestinal obstruction catheter and meglumine can treat EPISBO.
Aim:
To investigate the efficacy of an intestinal obstruction tube combined with meglumine diazo in treating EPISBO of colorectal cancer.
Methods:
Data from 60 patients with colorectal cancer and intestinal obstruction admitted to the Proctology Department of our hospital from April 2018 to May 2022 were collected and analyzed and divided into three cohorts according to different treatment regimens. Cohort A (n = 20) received a transnasal intestinal obstruction catheter with panumglumine, and cohort B (n = 20) received a transnasal intestinal obstruction catheter with liquid paraffin. Cohort C (n = 20) received oral treatment with meglumine. The clinical efficacy, first exhaust/defecation time, length of hospital stay, gastrointestinal decompression time, relief time of abdominal pain, and relief time of abdominal distension were compared among the three cohorts. The levels of C-reactive protein (CRP), tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6), monocyte chemotactic protein-1 (MCP-1), serum albumin, and transferrin were compared among the three cohorts before and after treatment. The occurrence of adverse reactions in the three cohorts was compared.
Results:
Compared with cohort C, the successful treatment rate of cohort A was significantly higher. There were statistically significant variations in the time of first exhaust/defecation, length of hospital stays, gastrointestinal decompression time, relief time of abdominal pain, and relief time of abdominal distention among the three cohorts. Compared with cohort C, cohort A's first exhaust/defecation time, hospitalization time, gastrointestinal decompression time, abdominal pain relief time, and abdominal distension relief time was reduced (P < 0.05). After treatment, serum CRP, TNF-α, IL-6, and MCP-1 expression levels increased, and serum albumin and serum transferrin levels increased in the three cohorts. The serum albumin level in cohort A was higher than in cohort C. Compared with cohort B and cohort C, the serum transferrin level in cohort A increased (P < 0.05). Compared with cohort C, the total incidence of adverse reactions in cohorts A and B was significantly higher (P < 0.05). The incidence of adverse reactions was similar between cohort A and cohort B.
Conclusion:
Using an ileus tube combined with meglumine diatrizoate can effectively treat postoperative inflammatory ileus obstructions after surgery colorectal cancer and improve prognosis, inflammatory response, and nutritional status.
... At the same time, the ileus catheter is a closed drainage system, which can accurately calculate the body fluid and electrolyte imbalance according to the drainage volume of the 2 catheters, and facilitate clinicians to quickly make adjustments. Zuo et al. reported that body fluid management and electrolyte balance monitoring are more convenient through the ileus catheter (19). The wide distribution of the 2 ileus catheters is more effective for the support arrangement of the whole intestinal canal and can prevent the adhesion and intussusception between the intestinal canal, which is similar to the fixed arrangement in the digestive tract. ...
Background:
Malignant intestinal obstruction refers to intestinal obstruction caused by advanced primary tumors or secondary metastatic malignant tumors. Because surgical treatment cannot significantly improve the life cycle, non-surgical treatment is mostly used to improve the symptoms of intestinal obstruction; transanal intestinal obstruction catheter and transnasal intestinal obstruction catheter are palliative therapies for decompression and drainage. Transanal intestinal obstruction catheter is mostly used for rectal and left colon obstruction. Transnasal intestinal obstruction catheter is mostly used for small intestinal obstruction. The two catheters are generally used alone according to the site of obstruction and clinical manifestations, and there are few reports on the combined use of the two catheters. We try to use the two catheters to treat patients with complex conditions and explore a better treatment strategy for malignant intestinal obstruction.
Case description:
Retrospective analysis From January 2016 to April 2022, 14 patients with advanced cancer were diagnosed as malignant intestinal obstruction by imaging data and clinical manifestations. Under the premise of no improvement in the symptoms of placement of a catheter, nasal ileus catheter combined with transanal ileus catheter was used for common decompression and drainage. The efficacy of combined catheterization was evaluated by comparing the differences in imaging data before and after catheterization, as well as analyzing the degree of relief and prognosis of intestinal obstruction symptoms; of intestinal obstruction symptoms was completely relieved in 4 of 14 patients combined catheterization, and spontaneous defecation and exhaust could be performed; intestinal obstruction symptoms were significantly relieved in 3 patients, reexamination of image air-fluid level was reduced by more than 70%, abdominal distension and abdominal pain were significantly relieved, and intermittent defecation and exhaust could be performed; intestinal obstruction symptoms were relieved in 3 patients, reexamination of image air-fluid level was reduced by 20-50%, abdominal distension and abdominal pain were relieved, and defecation and exhaust could not be performed; intestinal obstruction symptoms were not relieved in 4 patients.
Conclusions:
Combined application of transanal ileus catheter and transnasal ileus catheter decompression and drainage can be used as a palliative treatment to relieve the symptoms of malignant ileus.
