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Preoperatively, large radiopaque mass in the anterolateral aspect of the left lower leg.

Preoperatively, large radiopaque mass in the anterolateral aspect of the left lower leg.

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Citations

... (4,7,8) Traditionally, surgery was not advocated (9) given the associated complications, such as chronic sinus, infection, bleeding and amputation in extreme cases. (8) In those who had undergone surgical intervention, simple debridement and direct closure (8,10) or staged closure using skin grafts with NPWT application appears to be the most frequently used surgical technique. (11) Less frequently, skin graft application and the use of muscle to fill defects have also been described, although these procedures are much less common. ...
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The occurrence of calcific myonecrosis of the anterior compartment of the leg is rare. Common risk factors include a history of trauma, although little is known about the exact pathophysiology, latency period or triggering factors resulting in disease progression. Macroscopically, it begins with a single muscle being replaced by a fusiform calcified mass, which progresses peripherally. We present a rare case of a 7‐year history of chronic discharging sinus overlying the site with protruding calcified muscle and discuss the senior author's wound management strategy and surgical considerations. The initial approach used dressing applications to reduce wound exudate while obtaining repeated imaging for disease progression comparison. Repeated CT scans showed significant disease progression from a single solitary amorphous soft tissue calcification to disseminated scattered calcified myonecrosis. In planning such surgeries, extensive debridement and temporary wound coverage is the first stage. Subsequent definitive coverage includes skin grafting of the remaining defect.
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Unwanted, pathological calcifications can be categorized based on the initiating stimulus: trauma, tumor, disturbances of mineral metabolism, inflammation, or idiopathic (unknown) causes, and can be found in almost all tissues. For example, pulmonary calcifications are common asymptomatic findings, usually discovered on routine chest X-ray or at autopsy, and can occur in a wide variety of disorders, while vascular calcification (arteriosclerosis) is a common finding in elderly people, and causes heart disease and cerebral disorders. Several cellular components are involved in pathological calcifications, and there is some evidence suggesting pathological mineralizations and ossifications are regulated processes. In terms of structure and elemental analysis, there are no significant differences between pathological mineralization and bone formation. Calcifications may be present in biological tissue, as well as in synthetic graft material, for example in vascular prostheses.
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Heterotopic ossification (HO) is an important complication of head and spinal cord injuries (SCI). Pulse low-intensity electromagnetic field (PLIMF) therapy increases blood flow to an area of pain or inflammation, bringing more oxygen to that area and helps to remove toxic substances. The aim of this study was to determine the effect of PLIMF as prophylaxis of HO in patients with SCI. This prospective random control clinical study included 29 patients with traumatic SCI. The patients were randomly divided into experimental (n=14) and control group (n=15). The patients in the experimental group, besides exercise and range of motion therapy, were treated by PLIMF of the following characteristics: induction of 10 mT, frequency of 25 Hz and duration of 30 min. Pulse low-intensity electromagnetic field therapy started in the 7th week after the injury and lasted 4 weeks. The presence or absence of HO around the patients hips we checked by a plane radiography and Brookers classification. Functional capabilities and motor impairment were checked by Functional Independent Measure (FIM), Barthel index and American Spinal Injury Association (ASIA) impairment class. Statistic analysis included Kolmogorov-Smimrnov test, Shapiro-Wilk test, Mann Whitney Exact test, Exact Wilcoxon signed rank test and Fischer Exact test. Statistical significance was set up to p<0.05. At the end of the treatment no patient from the experimental group had HO. In the control group, five patients (33.3%) had HO. At the end of the treatment the majority of the patients from the experimental group (57.14%) moved from ASIA-A to ASIA-B class. Pulse low-intensity electromagnetic field therapy could help as prophylaxis of HO in patients with traumatic SCI.