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Potential Risks of Kidney Transplantation with Leigh Syndrome (LS)
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Background:
Leigh syndrome (LS) is a rare neurodegenerative mitochondrial disorder which typically presents in childhood but has a varied clinical course. Renal involvement such as proximal tubulopathy in patients with mitochondrial disorders has been described. However, end stage renal disease (ESRD) is uncommon and literature regarding patients...
Context in source publication
Context 1
... his neurological state was non-progressive with a more favourable prognosis, the possibility of transplantation was entertained. Specific perioperative risks related to his LS and possible negative effects of immunosuppressants on his neurological disease were considered and addressed as part of his pre-transplant evaluation (Table 1). ...
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