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Objective
To investigate the efficacy and safety of brodalumab, a fully human anti-interleukin-17 receptor A monoclonal antibody, in patients with axial spondyloarthritis (axSpA).
Methods
In a multicentre, placebo-controlled phase 3 study ( NCT02985983 ) conducted at 48 sites across Japan, Korea and Taiwan, patients with axSpA were randomised 1:1...
Ankylosing spondylitis (AS) is a rheumatologic disease characterized by ankylosis and ligament ossification of the spine with an elevated risk of vertebrae fractures at the cervical level or cervicothoracic junction. AS related cervical fractures (ASCFs) require early diagnosis and a treatment plan that considers the high risk for additional fractu...