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1. Plot of log10 serum vitamin D levels (nmol/L). Log10 25OHD and (a) FEV1/FVC (r 2 = 0.07, p < 0.01)*, (b) ECP µg/L (r 2 = 0.03, p = 0.09), (c) IgE IU/ml (r 2 = 0.01, p = 0.42), (d) hs-CRP mg/L (r 2 = 0.015, p = 0.23) and (e) BMI kg/m 2 (r 2 = 0.001, p = 0.78) in 100 Caucasian adults with moderate persistent asthma. *Denotes statistically significant (Linear regression). 

1. Plot of log10 serum vitamin D levels (nmol/L). Log10 25OHD and (a) FEV1/FVC (r 2 = 0.07, p < 0.01)*, (b) ECP µg/L (r 2 = 0.03, p = 0.09), (c) IgE IU/ml (r 2 = 0.01, p = 0.42), (d) hs-CRP mg/L (r 2 = 0.015, p = 0.23) and (e) BMI kg/m 2 (r 2 = 0.001, p = 0.78) in 100 Caucasian adults with moderate persistent asthma. *Denotes statistically significant (Linear regression). 

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Figure 1.1. Vitamin D metabolism and functions. 
Figure 1.3. Immunopathology in asthma. Allergens are presented to naive...
Figure 1.2. Genes involved in the vitamin D pathway. Vitamin D3 is...
Figure 1.6. Role of vitamin D, VDR and VDR polymorphisms in...
+34 Figure 2.11. A standard curve FIREILSA Human IL-10 on DS2....
A source of New Diagnostic Techniques for Asthma in Ireland
Thesis
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  • Nov 2017
The objective of this thesis is to set up new diagnostic methods for the study of asthma and related respiratory conditions in an Irish clinical laboratory, and to deepen our knowledge of the pathophysiology of this illness. Asthma currently affects 300 million individuals worldwide. Asthma healthcare costs continue to spiral upwards, incurring an...
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