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Pie chart representing the different classes of proteins that spectrin interacting proteins belong to. Classification of proteins into different classes was done with the help of PANTHER database.

Pie chart representing the different classes of proteins that spectrin interacting proteins belong to. Classification of proteins into different classes was done with the help of PANTHER database.

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Spectrin, the major component of the erythrocyte membrane skeleton is a key player in red cell biology. It has a significant role in signalling pathways and as such knowledge of spectrin interactors becomes crucial. Here we report the cytosolic interactome of human erythroid spectrin (ProteomeXchange id: PXD021525). This is to the best of our knowl...

Contexts in source publication

Context 1
... was found to significantly interact with heme-containing redox proteins, chaperones, lipid modulating proteins, membrane skeletal proteins, protein quality control maintenance machinery and signaling components. Figure 2 shows a pie chart of the different protein classes the interactome of spectrin can be divided into. A major class of spectrin interactor is seen to be redox active proteins, many of which are also heme containing. ...
Context 2
... enrichment signifies that the proteins are at least partially involved in a particular set of biological functions. The network is shown in Supplementary Figure S2. ...
Context 3
... was found to significantly interact with heme-containing redox proteins, chaperones, lipid modulating proteins, membrane skeletal proteins, protein quality control maintenance machinery and signaling components. Figure 2 shows a pie chart of the different protein classes the interactome of spectrin can be divided into. A major class of spectrin interactor is seen to be redox active proteins, many of which are also heme containing. ...
Context 4
... enrichment signifies that the proteins are at least partially involved in a particular set of biological functions. The network is shown in Supplementary Figure S2. ...