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Pictorial representation of health benefits of polyunsaturated fatty acids (PUFAs) in general.

Pictorial representation of health benefits of polyunsaturated fatty acids (PUFAs) in general.

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Recent developments in nutraceuticals and functional foods have confirmed that bioactive components present in our diet play a major therapeutic role against human diseases. Moreover, there is a huge emphasis on food scientists for identifying and producing foods with better bioactive activity, which can ultimately provide wellness and well-being t...

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... benefits include anticoagulant effect, help in thinning the blood, as well as antidepressant [100]. The health benefits of omega-3 fatty acids are well-known to scientific, clinical, and industry experts, with research examining effects on almost every body system and for numerous health conditions as mentioned in Table 1 and Figure 5. ...
Context 2
... anticoagulant effect, help in thinning the blood, as well as antidepressant [100]. The health benefits of omega-3 fatty acids are well-known to scientific, clinical, and industry experts, with research examining effects on almost every body system and for numerous health conditions as mentioned in Table 1 and Figure 5. ...

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... The presence of essential nutrients or bioactive compounds in the fish powder might have played a crucial role in promoting enhanced growth and development among the organisms in this group. 45 Overall findings underscore the positive impact of the fish powder feed on SGRs, highlighting its potential as a valuable dietary component for fostering accelerated growth in the studied organisms. ...
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The research focuses on assessing the efficacy of dried anchovy powder as a dietary supplement, examining its bioavailability and impact on growth and nutritional status. The study, centered on Wistar male rats, acknowledges anchovies for their rich essential nutrients and potential health benefits. Employing a meticulously controlled experimental design, the research exposes experimental animals to various dietary interventions by integrating dried anchovy powder. This study investigates the availability of vital nutrients like proteins, omega-3 fatty acids, vitamins, and minerals in the dried anchovy powder to Wistar male rats. The effects of dried anchovy powder on growth parameters, encompassing body weight, length, organ development, and the nutritional status of the rats, are explored. Examining hematological and biochemical markers provide insights into the overall health of the experimental subjects. Additionally, the research delves into potential mechanisms underlying the observed effects, including nutrient absorption and metabolism. The outcomes of this study offer valuable insights into the potential of dried anchovy powder as a nutritional supplement and its role in enhancing the nutritional status of the malnourished people of India. These findings may have a direct impact on dietary interventions aimed at improving human nutrition and health.
... Polymethoxylated flavones (PMF) are distinctive group of flavonoids that are solely present in citrus fruits, especially in orange and mandarin peels [221]. Polymethoxylated flavones have a wide spectrum of therapeutic effects like antioxidant potential, antithrombiotic properties, chemopreventive action, and cholesterollowering effects, as illustrated in Figures 5 and 6 [59,222]. Earlier studies have elaborated on their chemopreventive attributes against the biosynthesis of adhesion molecules, the appearance of tumor factor-R (TNFR), the spread of tumor to surrounding animal tissues by enhancing apoptosis, and the minimization lymphocytes propagation and platelet aggregation. ...
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The recent millennium has witnessed a notable shift in consumer focus towards natural products for addressing lifestyle-related disorders, driven by their safety and cost-effectiveness. Nutraceuticals and functional foods play an imperative role by meeting nutritional needs and offering medicinal benefits. With increased scientific knowledge and awareness, the significance of a healthy lifestyle, including diet, in reducing disease risk is widely acknowledged, facilitating access to a diverse and safer diet for longevity. Plant-based foods rich in phytochemicals are increasingly popular and effectively utilized in disease management. Agricultural waste from plant-based foods is being recognized as a valuable source of nutraceuticals for dietary interventions. Citrus peels, known for their diverse flavonoids, are emerging as a promising health-promoting ingredient. Globally, citrus production yields approximately 15 million tons of by-products annually, highlighting the substantial potential for utilizing citrus waste in phyto-therapeutic and nutraceutical applications. Citrus peels are a rich source of flavonoids, with concentrations ranging from 2.5 to 5.5 g/100 g dry weight, depending on the citrus variety. The most abundant flavonoids in citrus peel include hesperidin and naringin, as well as essential oils rich in monoterpenes like limonene. The peel extracts exhibit high antioxidant capacity, with DPPH radical scavenging activities ranging from 70 to 90%, comparable to synthetic antioxidants like BHA and BHT. Additionally, the flavonoids present in citrus peel have been found to have antioxidant properties, which can help reduce oxidative stress by 30% and cardiovascular disease by 25%. Potent anti-inflammatory effects have also been demonstrated, reducing inflammatory markers such as IL-6 and TNF-α by up to 40% in cell culture studies. These findings highlight the potential of citrus peel as a valuable source of nutraceuticals in diet-based therapies.
... Numerous therapeutic effects on human health, including anti-inflammatory, antioxidant, antibacterial, and anti-allergic properties, have been demonstrated for a broad variety of phytochemicals, including anthocyanidin terpenoids, phytosterols, carotenoids, limonoids, glucosinolates, polyphenols, isoflavonoids, phytoestrogens, flavonoids, etc. In addition to helping to maintain well-being and improve standard of living, these nutraceuticals also fight against significant modern-day medical [27]. Thus, low-cost nutraceuticals have consistently been in great demand, especially among those with a shaky economy or low incomes (Ashraf et al., 2020). ...
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The quest for novel functional food ingredients from natural sources is one of the most important discuss in food science and technology. Food industries dispose their valuable waste and some food industries re-process their wastes and used them as functional food ingredients, thereby developed their economy to survive in the neck cutting competition of the market. Enormous volumes of food processing by-products (FPBs) are produced from food manufacturing industries, accounting it as the second-largest quota of food waste generation. Fish known as ‘rich food for poor people,’ supplies good quality of fats, minerals vitamins and proteins to billions of populaces across the globe. However, the fish processing industry on daily basis generates huge wastes leading to the quest for management of these wastes. These wastes which can be referred to as by-products are generated during removal of head; gutting of the fish and during other secondary processing carried out either onboard in fishing vessels or at processing plants on the shores. Over the years there are bids for utilization of fish wastes and by products for production of functional food ingredients using bioactive compounds produced from them. This was aimed at reduction of processing waste, creation of sustainable economic boost, environmental safety while formulating value added functional food which could be of importance to human and animal health or wellbeing. By-products from fish processing such as blood, fleshy chunks of fatty fish, tails, liver from white lean fish, Fish heads, offal, viscera (gut, intestines, etc.), skin and shells have potentials utilization as raw materials for production of value-added functional food ingredients. Bioactive peptides isolated from various fish protein hydrolysates have reported to have several bioactivities such as immunomodulatory, antioxidative antihypertensive, antithrombotic, anticoagulant activities among others Hence from the review, the recovery of bioactive compound and utilization of these by-products are untapped sources for functional ingredients which can be applied in several aspects of food processing for the benefit of manufactures, supply series of nourishments, and consequently advancing the usefulness of the fish waste in consumers’ health and economic benefits of all stakeholders.
... There is strong scientific evidence for the positive effects of seafood consumption on human health, when seafood is included in a normal diet, at least twice a week (The Turkish Nutrition and Health Guide (TUBER), 2022). This is because fish is an important source of many nutrients, especially protein, retinol, vitamin D, vitamin E, iodine, selenium, and essential long-chain polyunsaturated fatty acids (Ashraf et al., 2020). It is important to determine the iodine content of foods in the daily diet in societies where iodine deficiency is observed, such as Turkey (Lall & Kaushik, 2021). ...
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Since there is currently a lack of scientific evidence regarding the iodine content of raw and cooked fish, this study assesses that of various raw and cooked (boiled, pan‐fried, and oven‐baked) fish samples, using inductively coupled plasma‐mass spectrometry (ICP‐MS), following alkaline extraction. The iodine content of the raw fish is found to be highest in anchovy (295.9 ± 4.2 μg/100 g) and lowest in salmon (90.1 ± 3.1 μg/100 g) in dried weight. Boiling is found to reduce the iodine content in all of the fish samples significantly, except the bonito and salmon (P < 0.05). Meanwhile, the iodine content per 100 g is found to increase significantly in the pan‐fried and oven‐baked fish. The highest percentage of one serving of cooked fish meeting recommended iodine requirement were determined in oven‐baking haddock (351.0%), while the lowest percentage of one serving (150 g) of cooked fish meeting the recommended iodine requirement were determined in boiled garfish (70.9%). The best means of meeting the recommended daily iodine requirement in all the fish species evaluated, except bluefish, is found to be oven‐baking, while boiling has the greatest effect on reducing the iodine content. As a result, fish samples from the eastern Black Sea region of Turkey are good sources of iodine and it was determined that their iodine content changes when various cooking methods are used.
... Marine-origin nutraceuticals include polysaccharides, peptides and proteins, polyunsaturated fatty acids (PUFAs), and other lipids, pigments, enzymes, phenolic compounds, minerals, and vitamins ( Fig. 1) [86][87][88]. The sources from which these compounds have been isolated include seaweeds [89], microalgae [90], fish, and a large group of marine invertebrates (arthropods, echinoderms, sponges, mollusks, cnidarians, lophophorates, marine worms, and the hemichordates) [91,92]. ...
... Besides, they are a rich source of bioactive peptides, biomolecules derived from fish protein hydrolysates that have shown numerous biological activities (antioxidant, antimicrobial, antihypertensive, antiproliferative, immunomodulatory, antidiabetic, etc.). For this reason, they are considered biomolecules with positive health effects and potential therapeutic applications [91]. Proteins and peptides derived from marine invertebrates, squids, snails, shellfish, and jellyfish have shown antioxidant, anti-inflammatory, anticancer, antiviral, antibacterial, immunomodulatory, and antihypertensive activities [99]. ...
... Besides, they have neuroprotective effect, and they stimulate neurodevelopment and neurotransmission in humans. Fatty fish, microalgae, seaweeds, krill, and fungi are significant sources of these fatty acids [100][101][102][103]. Like humans, fish cannot synthesize PUFAs, but they obtain them from feed (krill or algae that they consume) [91]. Lipids, including PUFAs, are mostly extracted from fish and marketed as fish oil. ...
Chapter
The marine resource hosts wide biodiversity, regarded as a rich source of diverse bioactive compounds, which are widely investigated for their bioactive composition and nutraceutical applications having several health benefits. Several in vitro and in vivo studies have reported the impacts of marine bioactive compounds in controlling several lifestyle disorders. Based on their high bioactive compounds and nutraceutical value, their extraction techniques are known to influence their bioactivity widely. The present chapter summarizes the knowledge on novel extraction technologies of bioactive compounds from marine sources; further, based on their bioactivity and nutraceutical property, their ability to modulate development of several disorders is addressed. Besides, the chapter covers food application of derived bioactive compounds to develop nutraceutical foods.
... Besides supporting human body growth and function, bioactive compounds in seafood also have therapeutic potential that help alleviate and manage disease conditions [2]. Fish occupies a prominent place among marine products and is considered an afordable source of protein and a source of nutraceutical importance [3]. Moreover, fsh and other marine species comprise about half of the total biodiversity and are also a valuable source of novel bioactive compounds that improve human health. ...
... Recent critical reviews on bioactive compounds and therapeutics from marine products and fsh have been conducted [1][2][3]. Tese reviews revealed that fshes and fsh products ofer numerous nutritional and unique health benefts, which result from their nutrients and bioactive compounds. Tese compounds confer nutritional importance and therapeutic efects against chronic diseases such as diabetes, obesity, cancer, cardiovascular diseases, infection, infammatory and oxidative stress-related ailments, hepatic and brain functions, and immune system disorders. ...
... Tere is also a need to increase awareness of the quality of proteins, omega-3 fatty acids, and other compounds inherent in fsh and fsh-based food products and nutraceuticals like fsh oils. Te composition of fsh oils, from fatty acids to other compounds, has been reported [1][2][3]. Fatty acids in fsh oils include PUFA (eicosapentaenoic acid/EPA, docosahexaenoic acid/DHA, arachidonic acid, etc.), monounsaturated fatty acids/MUFA (gondoic acid, palmitoleic acid, oleic acid, etc.), and saturated fatty acids/SFA (palmitic acid, stearic acid, etc.). PUFA in fsh oils, refected strongly by bioactive lipids, comprises both EPA and DHA which are known as omega-3 fatty acids. ...
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Due to their signifcant health benefts, fsh oils have garnered increasing interest in recent decades. However, Cameroon's fsh oil market remains insignifcant, and the few available products are imported, despite the country's abundant marine resources. Additionally, research on Cameroonian fsh oils is relatively recent and scarce. Terefore, this manuscript provides an overview of research on fsh oils in Cameroon, focusing on their physicochemical characteristics, as well as their nutritional and biological properties. As of March 2023, 26 studies on fsh oils in Cameroon have been published, with a focus on 23 species collected in the littoral, far-north, and west regions of Cameroon. Filets were the main parts used, and the Bligh Dyer and Soxhlet methods were the primary oil extraction techniques. Depending on the species, tissues, and extraction methods, oil contents ranged from 4.57% to 32.10% dry matter or yielded 0.36% to 66.83% wet weight. Tese oils generally meet recommended standards for markers of acidity and oxidation. Fatty acid profles from 16 species showed a total of 48 fatty acids, including those that are benefcial to human health. Oils from eight species were found to signifcantly reduce weight, hyperlipidemia, hyperglycemia, hepatomegaly, and adipomegaly, while four species showed activity against bacteria responsible for food poisoning. Future work should include all fsh species found in Cameroon, with a focus on by-products, and explore the physicochemical, functional, nutritional, and biological properties of these oils.
... Compared with plant proteins, animal proteins are easier to digest and as such provide more bioavailable amino acids to promote the synthesis of protein in the muscles [8]. Among high quality proteins, fish protein is extremely digestible and balances many regulatory factors, as well as being a plentiful source of animal protein and essential amino acids [9,10,11]. Fish protein has been reported to promote skeletal muscle hypertrophy and protein synthesis by activating the Akt/mTOR signaling pathways [12]. In Taiwan, fish soup is a traditional dietary remedy for pregnant women or frail patients in need of fatigue relief and quick recovery [13]. ...
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Background:Fish protein supplementation may maintain muscle strength and prevent sarcopenia as it contains a complex array of macro- and micronutrients essential for building the skeletal muscle. Objective:The aim of this study was to evaluate the influence of perch essence (PE) supplementation on muscle mass and muscle function of through human and cell model. Methods:The open label clinical trial was conducted to assess the therapeutic effect of PE on muscle mass improvement. The mouse skeletal muscle cell (C2C12) model of muscle atrophy was analyzed for cell viability. Results:Our results showed PE contained abundant branched chain amino acid, taurine, hydroxyproline and collagen. After one month of supplementation with PE in our human model, there was a significant increase in muscle mass in the whole body and all parts of the body, with an increase of 1.55 % in the whole body, 1.79% in the trunk, 1.64% in the arms and 1.38% in the legs. The percentage of subcutaneous fat in the trunk, arms and legs also decreased significantly by 2.49%, 3.21% and 3.40% respectively. PE supplementation also improves muscle grip strength, especially with the dominant hand. The cell model results demonstrated that PE could effectively prevent skeletal muscle cell from death induced by dexamethasone. Conclusion:This study suggests that the branched chain amino acids, taurine, hydroxyproline and collagen in PE have the potential to serve as a good source of dietary supplements for the improvement of skeletal muscle mass and strength through cell protection.Keywords:branched chain amino acid, collagen, perch, skeletal muscle, sarcopenia
... The beautiful coloration of different seafood species, such as fish, crustaceans, mollusks, and seaweeds, is due to the presence of various coloring agents commonly known as carotenoids [3]. Natural carotenoids in seafood by-products have strong health-beneficial activities [127]. The common carotenoids obtained from seafood by-products are astaxanthin, cantaxanthin, zeaxanthin, β-carotene, etc. [127]. ...
... Natural carotenoids in seafood by-products have strong health-beneficial activities [127]. The common carotenoids obtained from seafood by-products are astaxanthin, cantaxanthin, zeaxanthin, β-carotene, etc. [127]. Although carotenoids have biological activities, astaxanthin (3,3 -dihydroxy-β, β -carotene-4,4 -dione) (red-pink color) has anticancer, neuroprotective, and strong antioxidant activities [14]. ...
... Astaxanthin is also beneficial for improving cardiovascular health and regulating blood pressure. Owing to their highly beneficial activities, marine carotenoids are used in food products, pharmaceuticals, and cosmetics [127]. Several carotenoids are used as preservatives in cosmetic products like ions and sun-protection creams [3]. ...
Article
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Fishery production is exponentially growing, and its by-products negatively impact industries' economic and environmental status. The large amount of bioactive micro-and macromolecules in fishery by-products, including lipids, proteins, peptides, amino acids, vitamins, carotenoids, enzymes, collagen, gelatin, chitin, chitosan, and fucoidan, need to be utilized through effective strategies and proper management. Due to the bioactive and healthy compounds in fishery discards, these components can be used as functional food ingredients. Fishery discards have inorganic or organic value to add to or implement in various sectors (such as the agriculture, medical, and pharmaceutical industries). However, the best use of these postharvest raw materials for human welfare remains unelucidated in the scientific community. This review article describes the most useful techniques and methods, such as obtaining proteins and peptides, fatty acids, enzymes, minerals , and carotenoids, as well as collagen, gelatin, and polysaccharides such as chitin-chitosan and fucoidan, to ensure the best use of fishery discards. Marine-derived bioactive compounds have biological activities, such as antioxidant, anticancer, antidiabetic, anti-inflammatory, and antimicro-bial activities. These high-value compounds are used in various industrial sectors, such as the food and cosmetic industries, owing to their unique functional and characteristic structures. This study aimed to determine the gap between misused fishery discards and their effects on the environment and create awareness for the complete valorization of fishery discards, targeting a sustainable world.
... Carotenoids exist in a significant amount as natural pigments in pink red-, orange-and yellowcolored crustaceans which have been utilized as a skin preservative in cosmetics as they have strong antioxidant properties. It has also been mixed with several other antioxidants to form creams and lotions for UV protection [169]. To further enhance the topical properties of these active ingredients, the combination of the active ingredients with other compounds yielded better results. ...
... Carotenoids present in crustaceans can help to mitigate the oxidative stress in our body and also help to reduce chronic diseases including cardiovascular disease and cancer [164]. Carotenoids also find applications in cosmetics as they have strong antioxidant properties which are alone or with other antioxidants serving as creams and lotions for UV protection [169]. The anti-microbial packaging application of chitosan has received much importance in recent times. ...
Article
The unscientific disposal of the most abundant crustacean wastes, especially those derived from marine sources, affects both the economy and the environment. Strategic waste collection and management are in need of the hour. Sustainable valorization approaches are played a crucial role in solving those issues as well as generating wealth from waste. The shellfishery wastes are rich in valuable bioactive compounds such as chitin, chitosan, minerals, carotenoids, lipids, and other amino acid derivatives. These value-added components possessed pleiotropic applications in different sectors viz., food, nutraceutical, cosmeceutical, agro-industrial, healthcare, and pharmaceutical sectors. The manuscript covers the recent status, scopes of shellfishery management, and different bioactive compounds obtained from crustacean wastes. In addition, both sustainable and conventional routes of valorization approaches were discussed with their merits and demerits along with their combinations. The utilization of nano and microtechnology was also included in the discussion, as they are becoming prominent research areas in recent years. More importantly, the future perspectives of crustacean waste management and other potential valorization approaches that can be implemented on a large scale.
... Fish and fishery products are essential components of a healthy diet [141,142]. They contain several essential nutrients, including omega-3 fatty acids, are low in saturated fat and are a cheap source of animal protein in developing countries [143,144]. The diverse ecosystems of the Niger Delta are potential hotspots for numerous species and economic trends, with local and rural communities engaging in commercial fishing [1]. ...
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The Niger Delta environment is under serious threat due to heavy metal pollution. Many studies have been conducted on the heavy metal contamination in soils, water, seafood and plants in the Niger Delta ecosystem. However, there is a lack of clear understanding of the health consequences for people and strategies for attaining One Health, and a dispersion of information that is accessible. The study focused on investigating the contamination levels, distributions, risks, sources and impacts of heavy metals in selected regions of the Niger Delta. Prior studies revealed that the levels of certain heavy metals, including Cd, Pb, Cu, Cr, Mn, Fe and Ni, in water, sediment, fish and plants in most Niger Delta ecosystems were higher than the acceptable threshold attributed to various anthropogenic stressors. In the reviewed Niger Delta states, ecosystems in Rivers state showed the highest concentrations of heavy metals in most sampled sites. Groundwater quality was recorded at concentrations higher than 0.3 mg/L World Health Organization drinking water guideline. High concentrations of copper (147.915 mg/L) and zinc (10.878 mg/L) were found in Rivers State. The heavy metals concentrations were greater in bottom-dwelling organisms such as bivalves, gastropods and shrimp than in other fishery species. Heavy metal exposure in the region poses risks of communicable and non-communicable diseases. Diverse remediation methods are crucial to reduce contamination levels, but comprehensive strategies and international cooperation are essential to address the health hazards. Actively reducing heavy metals in the environment can achieve One Health objectives and mitigate disease and economic burdens.