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Photomicrographs of histological sections of the thyroid gland stained with H&E. Control group (a, a1) showing follicles (F), parafollicular cells (P), follicular epithelium lined with squamous to columnar cells (arrow), central lumen filled with colloid (CO), and a part of parathyroid gland (Pa) appeared. In the 10%EF group (b, b1) showing small retention of lobular architecture, follicular cells (F) filled with colloid (CO), and follicular epithelial cells containing flattened nuclei (arrow). The 50%EF group (c, c1) showed the formation of microfollicles (curved arrow), pale colloid (CO), hemorrhage (He), flatness of follicular epithelium (arrow), and the appearance of pyknotic nuclei (PN). In the 100%EF group (d, d1) numerous microfollicles (curved arrow), absence of colloid (CO) in most follicles, hyperplastic epithelium of follicular cells (arrowhead), inflammatory cells (IC), presence of migrated and isolated follicular cells (zigzag arrow), hemorrhage (He), and pyknotic nucleus (PN) were observed. For 100%EF + AG group (e, e1) follicular cells of various sizes (F) with lumen filled mostly with colloids (CO), hemorrhage (He), and inflammatory cells (IC) were observed and the nuclei of the follicular epithelium appeared rounded (arrow) with some pyknotic cells (PN)

Photomicrographs of histological sections of the thyroid gland stained with H&E. Control group (a, a1) showing follicles (F), parafollicular cells (P), follicular epithelium lined with squamous to columnar cells (arrow), central lumen filled with colloid (CO), and a part of parathyroid gland (Pa) appeared. In the 10%EF group (b, b1) showing small retention of lobular architecture, follicular cells (F) filled with colloid (CO), and follicular epithelial cells containing flattened nuclei (arrow). The 50%EF group (c, c1) showed the formation of microfollicles (curved arrow), pale colloid (CO), hemorrhage (He), flatness of follicular epithelium (arrow), and the appearance of pyknotic nuclei (PN). In the 100%EF group (d, d1) numerous microfollicles (curved arrow), absence of colloid (CO) in most follicles, hyperplastic epithelium of follicular cells (arrowhead), inflammatory cells (IC), presence of migrated and isolated follicular cells (zigzag arrow), hemorrhage (He), and pyknotic nucleus (PN) were observed. For 100%EF + AG group (e, e1) follicular cells of various sizes (F) with lumen filled mostly with colloids (CO), hemorrhage (He), and inflammatory cells (IC) were observed and the nuclei of the follicular epithelium appeared rounded (arrow) with some pyknotic cells (PN)

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The effluents discharged from Mansoura Company for Resins and Chemicals Industry were evaluated for drinking and irrigation purposes. Calcium-alginate beads were used for effluents treatment in this study. Young male rats were also allowed to drink effluents at different concentrations (10%, 50%, 100%) and treated 100% effluents with calcium-algina...

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