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Acantholippia salsoloides (Verbenaceae) is an aromatic plant widespread in the Andean region. The infusion (leaves and flowers) is widely used as a digestive stimulant as well as for the treatment of various diseases in traditional medicine. A. salsoloides attributes its common name “rica-rica” to the fresh and sweet fragrance of the plant. In this...
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Verbenaceae species are widely used in the traditional medicine to treat tumors, liver pathologies, hypertension and nervous hepatitis. The aim of this present study was to evaluate phenols and flavonoids chromatographic profile of 5 Verbenaceae species directed against antioxidant activities. 3 types of extracts were used in this evaluation such a...
Citations
... Each EO was performed in triplicate. [33] Mean values were compared using two way ANOVA and Tukey test to determine differences with statistical significance. ...
... [35][36] Minimum inhibitory concentration (MIC) was determined by employing broth microdilution methods based on the Clinical and Laboratory Standards Institute (CLSI) guidelines, reference document M100, with minor modifications. [33,38] Briefly, the suspensions of bacteria cultures were prepared in ampoules containing NaCl 0.85 % suspension medium. After adjusting the turbidity to 0.5 McFarland, suspensions were diluted in Mueller Hinton broth medium (MHB, Britania SA, Argentina) until the final bacterial density of 1.5 × 10 6 CFU/mL. ...
The purpose of this study was to investigate essential oils (EOs) from leaves of Elionurus muticus growing in Northeastern Argentina regarding their physicochemical profiles as well as their biological potential. Roots of a selected E. muticus population were investigated too. For this purpose, EOs of fresh materials were obtained by steam distillation and the chemical composition was characterized by gas chromatography GC/MS-FID. Antibacterial, antioxidant and eco-toxicity activities of the essential oils (EOs) were tested by in vitro assays. The EOs showed three E. muticus chemotypes: citral (neral + geranial), acorenone + bisabolone, acorenone + gera-nial. EO of roots of citral population contains mainly acorenone derivatives. EOs have high antibacterial effect against Staphylococcus aureus, being found minor antibacterial effect against Gram-negative bacteria. The half-maximal inhib-itory concentration of EOs against DPPH * were 7.1-30.0 mg/ mL and the eco-toxicity was high with LD 50 < 39 μg/mL. Based on the findings, given the high variability in their chemical composition and biological activity of E. muticus EO and the promising yields, it could be potentially chosen for industrial applications.
... Malaysia Leaves and barks [79] Alpinia blepharocalyx K. Zingiberaceae Vietnam Seeds [80] Chrysanthemum morifolium Asteraceae Korea Not reported [81] Scutellaria baicalensis Labiatae Mentha longifolia (L.) Lamiaceae Hungary Leaves and flowers [82,83] Acantholippia salsoloides Verbenaceae Portugal Leaves and flowers [84] Capsicum Cultivars Solanaceae Germany Leaves [85] Lavandula stoechas Lamiaceae Greece Not reported [86] Lonicera japonica flos Caprifoliaceae China Not reported [87] Elsholtiza bodinieri Lamiaceae China Not reported [55] Aronia melanocarpa Rosaceae Poland Leaves and fruits [88] Aronia arbutifolia Rosaceae Aronia prunifolia Rosaceae Angelica keiskei Apiaceae Korea Not reported [90] Salvia plebeia R. Br. Lamiaceae Korea Aerial parts [89] Lonicera japonia Thunb. ...
... It was by-product from S. dracocephaloides Boiss. obtained with the maceration method using 1 H and 13 C NMR [78], A. blepharocalyx K. using MS, IR, and NMR analysis [80], M. longifolia (L.) leaves and flowers obtained with soxhlet, maceration, and ultrasonic using the HPLC-DAD method [82], C. morifolium and Scutellaria baicalensis using LC-MS/MS [81], A. salsoloides using Ion-trap mass spectrometry with flame ionization detection via gas chromatography [84] C. Cultivars [85], L. stoechas [86], L. japonica flos [87], leaves and fruits of A. melanocarpa, A. arbutifolia, and A. prunifolia using HPLC-DAD [88]. ...
Cynaroside is a flavonoid, isolated from several species belonging to the Apiaceae, Poaceae, Lamiaceae, Solanaceae, Zingiberaceae, Compositae and other families and it can be extracted from seeds, roots, stems, leaves, barks, flowers, fruits, aerial parts, and the whole plant of these species. This paper discloses the current state of knowledge on the biological/pharmacological effects and mode of action to better understand the numerous health benefits of cynaroside. Several research works revealed that cynaroside could have beneficial effects on various human pathologies. Indeed, this flavonoid exerts antibacterial, antifungal, antileishmanial, antioxidant, hepatoprotective, antidiabetic, anti-inflammatory, and anticancer effects. Additionally, cynaroside exhibits its anticancer effects by blocking MET/AKT/mTOR axis by decreasing the phosphorylation level of AKT, mTOR, and P70S6K. For antibacterial activity, cynaroside reduces biofilm development of Pseudomonas aeruginosa and Staphylococcus aureus. Moreover, the incidence of mutations leading to ciprofloxacin resistance in Salmonella typhimurium was reduced after the treatment with cynaroside. In addition, cynaroside inhibited the production of reactive oxygen species (ROS), which reduced the damage to mitochondrial membrane potential caused by hydrogen peroxide (H2O2). It also enhanced the expression of the anti-apoptotic protein Bcl-2 and lowered that of the pro-apoptotic protein Bax. Cynaroside abrogated the up-regulation of c-Jun N-terminal kinase (JNK) and p53 protein expression triggered by H2O2. All these findings suggest that cynaroside could be used to prevent certain human diseases.
