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Patient 1. (A) Tumor size of the AM was 2.5 cm. The tumor shape was round and smooth, and fatty tissue was detected around the tumor by CT (→). (B) According to the pathological findings, the adrenal tumor was clear-cell carcinoma, as well as the primary malignancy, and the border between the tumor and the surrounding fatty tissue was evident.
Source publication
The present study aimed to clarify decision-making factors based on imaging for laparoscopic adrenalectomy (LA) or open adrenalectomy (OA) for adrenal metastasis (AM) based on our previous experience. From November 2003 to November 2006, 11 adrenalectomies were performed for AM for malignancies such as lung cancer, renal cell carcinoma (RCC) and br...
Contexts in source publication
Context 1
... of a large size and with a cystic component. A representa- tive case of the first pattern was patient 1. Patient 1 received radical nephrectomy for right RCC. AM was diagnosed at 16 months after radical nephrectomy. The tumor size of the AM was 2.5 cm. The tumor shape was round and smooth and fatty tissue was detected surrounding the tumor by CT (Fig. 2A). We performed resection including the surrounding fat. Fatty tissue is required to detach the tumor and proximal organs. We performed LA for the tumor without any adhesion. According to the pathological findings, the adrenal tumor was diagnosed as clear-cell carcinoma, and as the primary malig- nancy, and the border between the tumor ...
Context 2
... the surrounding fat. Fatty tissue is required to detach the tumor and proximal organs. We performed LA for the tumor without any adhesion. According to the pathological findings, the adrenal tumor was diagnosed as clear-cell carcinoma, and as the primary malig- nancy, and the border between the tumor and the surrounding fatty tissue was evident (Fig. ...
Similar publications
Renal cell carcinomas can metastasize to almost any organ. Metachronous solitary contralateral adrenal metastasis from renal cell carcinoma is, however, very rare. Surgical resection is appropriate in isolated metastatic renal cell carcinoma, but the metastasectomy in the case of contralateral adrenal metastasis of renal cell carcinoma has not been...
Citations
... The aim of metastatic breast cancer treatment is to improve the quality of the patients' life and prolong their survival. LA has become the treatment of choice for adrenal gland tumors because it has advantages such as speed recovery and early discharge from hospital [12]. Yoshitomi and Tsuji [13] have reported a patient with adrenal metastasis from breast cancer who underwent adrenalectomy and toremifene endocrine therapy and was followed by 28 months of recurrence-free survival. ...
The adrenal gland is a frequent site for metastasis, and the majority of the metastatic lesions of the adrenal gland normally originate from lung cancer, colon cancer, renal cell carcinoma, and melanoma. However, adrenal gland metastasis from breast invasive mucinous carcinoma is extremely rare. This report described a rare case of right adrenal gland metastasis in a 48-year-old female, who was diagnosed with breast invasive mucinous carcinoma and underwent right modified radical mastectomy with axillary lymph node dissection 5 years previously. A mass located on the right adrenal gland was detected during a routine examination 2 months ago. The patient was asymptomatic and adrenal gland MRI revealed a mass in the right adrenal gland. Definitive preoperative diagnosis failed to be established. Right adrenal gland laparoscopic adrenalectomy was performed and the diagnosis of adrenal gland metastasis of breast carcinoma was confirmed by pathological and immunohistochemical examination, especially ER, PR, GATA3, and HER-2. The patient remained in good condition by the time of writing.
... Laparoscopic adrenalectomy is widely applied to adrenal gland tumors. However, the gold standardization in adrenal cancer metastasis remains controversial [12]. ...
Invasive ductal carcinoma (IDC) is the most common histopathological type of breast cancer, accounting for up to 85% of all invasive breast carcinomas [1]. It spreads usually to the bone first. Solitary metastasis is commonly located in the lung, liver or brain [2]. Adrenal glands locations are extremely rare [3]. We report a case of isolated metachronous right adrenal metastasis, diagnosed four years after breast IDC management. The aim is to highlight clinical, diagnostic and therapeutic characteristics of this entity
... Laparoscopic adrenalectomy is widely applied to adrenal gland tumors. However, the gold standardization in adrenal cancer metastasis remains controversial [12]. ...
... Sixteen studies were excluded because the number of patients was less than 3. Nine studies were excluded because they were review articles. Finally, 13 studies were found eligible for inclusion according to our criteria for considering studies in this review [7,[14][15][16][17][18][19][20][21][22][23][24][25] (Fig. 1). ...
OBJECTIVES
This systematic review and pooled analysis investigated outcomes and prognostic factors in Non-small-cell lung cancer (NSCLC) patients who underwent surgical treatment for an isolated adrenal metastasis and the primary NSCLC.
METHODS
A literature search of PubMed, Embase and Cochrane Library databases was conducted for relevant retrospective studies in patients with NSCLC and isolated adrenal metastatic lesions treated with lobectomy or pneumonectomy and adrenalectomy. Outcome measures were overall, 1-, 2- and 5-year survival rates stratified by synchronous versus metachronous adrenal metastasis and according to lymph node status, pathology and relative location of the metastasis to the primary tumour. Kaplan?Meier survival curves were generated and differences in survival were assessed by a log-rank test.
RESULTS
Thirteen studies involving 98 patients were included in this analysis. The median overall survival was 18 months, and the 1-, 2- and 5-year survival rates were 66.5, 40.5 and 28.2%, respectively. Patients with metachronous adrenal metastasis had a significantly better prognosis than patients with synchronous adrenal metastasis (P < 0.05). Patients classified as negative for lymph node metastasis had a significantly better prognosis than patients classified as positive for lymph node metastasis (P < 0.05). Pathology (squamous carcinoma versus adenocarcinoma) and the relative location of the metastasis to the primary tumour (ipsilateral adrenal metastasis or contralateral adrenal metastasis) had no significant influence on prognosis.
CONCLUSIONS
NSCLC patients with isolated adrenal metastasis undergoing surgical treatment for the primary tumour and adrenal metastasis could achieve a significant survival benefit, especially if they have metachronous adrenal metastasis or are negative for lymph node metastasis.
... It is also important to avoid port-site metastasis and carcinomatosis when performing LA. Therefore, whether LA can be widely applied to adrenal gland tumors remains controversial (13). If it is necessary to perform adrenalectomy, particularly for bilateral adrenal gland metastasis, partial adrenalectomy is an alternative and ideal treatment strategy. ...
The majority of the metastatic lesions of the adrenal gland normally originate from lung cancer, colon malignant tumor, renal cell carcinoma and melanoma. However, adrenal gland metastasis that metastasize from breast invasive ductal carcinoma are extremely rare. The present study reported a rare case of left adrenal gland metastasis in a 35-year-old female who was diagnosed as breast carcinoma 5 years ago with a mass located on the left adrenal gland, which was detected during a routine examination. The patient was asymptomatic and adrenal gland computed tomography revealed a mass in the left adrenal gland. Definitive preoperative diagnosis failed to be established. Left adrenal gland laparoscopic adrenalectomy was performed and the diagnosis of adrenal gland metastasis of breast invasive ductal carcinoma was confirmed by pathological and immunohistochemical examination. The patient remained in good condition by the time of writing.
