Pathological assessment of HE-stained sections. The well-differentiated squamous cell carcinoma is obviously keratinized (indicated with white arrow). No urothelial carcinoma or renal cell carcinoma component was found in the section. HE, hematoxylin-eosin.

Pathological assessment of HE-stained sections. The well-differentiated squamous cell carcinoma is obviously keratinized (indicated with white arrow). No urothelial carcinoma or renal cell carcinoma component was found in the section. HE, hematoxylin-eosin.

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This is the first case report of the outcomes of systemic chemotherapy in a patient with locally advanced renal squamous cell carcinoma, a rare tumor, as well as the first next generation sequencing study of this rare tumor. The patient's main symptoms were fever and low back pain. Initial positron emission tomography and computed tomography (PET-C...