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ABSTRACT: Situs inversus totalis is is a congenital anomaly associated with various visceral abnormalities, but there is no data about the relationship between secondary biliary cirrhosis and that condition. We here present a case of a 58 year-old female with situs inversus totalis who was admitted to our clinic with extrahepatic cholestasis. After...
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Context 1
... thoracic computed tomography (CT), dextrocardia and scars of previous pulmonary infections were observed ( Figure 1). A paranasal sinus CT showed the findings of chronic sinusitis ( Figure 2). In transab- dominal ultrasonography (US), situs inversus totalis, mild heterogeneous liver parenchyma with grade I hepatostea- tosis, choledoc dilatation (11 mm) and mild splenome- galy were determined. ...Similar publications
Background
CXCR6 + CD8 + T cells have been implicated in the pathogenesis of various liver and autoimmune diseases. However, their involvement in Primary Biliary Cholangitis (PBC) has not been eluciated.
Methods
We used immunohistochemistry and flow cytometry to quantify CXCR6 + CD8 + T cells in hepatic tissue and peripheral blood samples obtained...
Citations
... Así también el SIT se asocia a anomalías anatómicas de la vena cava, del tronco celiaco y de la irrigación de la vesícula biliar como arteria cística doble, inferior o posterior 8,14,25,33 . También se han descrito algunas malformaciones y anomalías de la vía biliar que incluyen quistes del colédoco, atresia de la vía, colangitis esclerosante y cirrosis biliar secundaria [34][35][36][37] . Por estas razones sugerimos que en el estudio preoperatorio de estos pacientes se incluya una resonancia magnética de la vía biliar, la cual además de descartar estas anomalías contribuiría a delinear la anatomía quirúrgica y a planificar la cirugía. ...
Introducción:
El situs inversus totalis es una condición congénita en la cual los órganos torácicos y abdominales se encuentran en posición contraria a la posición habitual. En la literatura quirúrgica internacional se encuentran publicados no más de 55 casos de colecistectomía en pacientes con situs inversus totalis. La resolución laparoscópica de una paciente en nuestra Institución nos permite revisar esta particular condición patológica.
Caso Clínico:
Paciente femenino de 43 años de edad hospitalizada por una colecistitis aguda la cual es resuelta por vía laparoscópica sin incidentes.
Material y Método:
Se resume la literatura actual mediante una extensa revisión en PubMed de los reportes más relevantes. Considerando que todos los artículos publicados son casos clínicos o pequeñas series de casos, se presentan los resultados de esta revisión en tablas con estadística descriptiva básica.
Discusión:
Se discuten las características generales de estos pacientes, la presentación clínica, diagnóstico y técnica quirúrgica.
Conclusión:
La colecistectomía laparoscópica constituye el estándar de oro en pacientes con situs inversus y patología biliar, la cual debe ser realizada por un cirujano experimentado acomodando los trocares apropiadamente, debido a las dificultades técnicas que se encuentran en estos pacientes por las anomalías anatómicas propias de esta condición. El diagnóstico radiológico actual permite la planificación del abordaje y del procedimiento quirúrgico apropiado para cada paciente.
... Situs inversus totalis (SIT) is defined as a complete inversion-transposition of all thoracic and abdominal organs, so the position of organs in these cavities looks like a mirror image of normally positioned organs [1,2]. SIT is a rare, congenital condition with the incidence of 0.02%, more frequent in females than in males with the ratio of 3:2, and it isn't associated with race [3,4]. The structure and functioning of all organs are preserved, so SIT is asymptomatic condition most frequently determined by chance during some diagnostic procedures, such as electrocardiography (ECG), roentgenography (Rdg), ultrasound (US), computerized tomography, and sometimes it's discovered postmortem during autopsy [5]. ...
Introduction. Situs inversus totalisis defined as a total inversion-transposition of all thoracic and abdominal organs, so the position of organs in these cavities is like a mirror image of normally positioned organs. Case report. The study presents a case of a 49-year-old female with chest pain and hemodynamic instability. She was hospitalized at University Clinical Center of Kragujevac where she passed away two days later. During hospitalization, determined the condition of situs inversus totalis, but she was not diagnosed with myocardial infarction. After autopsy it was concluded that the cause of death was myocardial infarction Conclusion. In patients with situs inversus totalis special attention should be paid to conducting and interpreting diagnostic procedures and conducting therapeutic procedures as well, since inverse anatomy of some structures demands different approach than usual.
... As a birth defect in newborn infants, it has an estimated incidence of 1/15 000 to 10 000 cases in live births, with a male/female ratio of 3:2. 1 The cause of situs inversus (SI) is unknown. More than one genetic mutation, including gene mutations that cause ciliopathy and cystic renal diseases, were implicated in its etiopathogenesis. 2 There is no evidence to suggest that SI predisposes to cholelithiasis or that cholelithiasis occurs with greater frequency in this population. ...
