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Background: Orthostatic hypotension(OH) is a sustained reduction of systolic blood pressure of at least 20mmHg or diastolic blood pressure of at least 10mmHg within three minutes of standing from supine position. Increase in the elderly population has been accompanied by a rising number of injuries and accidents due to physical disabilities associa...
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... was no statistically significant difference in the mean ages of participants with and without OH. The difference between the mean ages of males and females is statistically significant (T-test = 2.485, p=0.013) Table 3: This table shows the relationship between OH and BMI .Greater proportion of those with OH were on normal range BMI 31(52.5%) while those who are underweight and obese had lower prevalence of OH . ...Similar publications
This cross-sectional study investigated the epidemiology and risk factors associated with orthostatic hypotension (OH) and its severity in older adults residing in the Jizhou community of Tianjin and the Jimei community of Xiamen. The study, conducted from March to September 2019, involved adults aged over 60. A comprehensive questionnaire survey w...
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... Its hypotensive action comes from the reduction of the activity of the renin-angiotensin-aldosterone system caused by the β1 receptor blockade in the juxtapoclarular renal cells. Nebivolol can also cause orthostatic hypotension in response to changes induced by intravascular volume severity due to negative inotropic and chronotropic effects of β1 blockers 36 . All of this reduces the capacity of the heart to increase heart rate and cardiac output, increasing the risk of falls 33 . ...
The combination of types of medications can compromise the regulation of body balance in older adults. This study evaluated the effect of continuous use drugs on the sensory regulation of static balance in elderly women who regularly practice the Pilates method with and without a history of falls and estimate the risk of falls in this population. Cross-sectional study, carried out with 94 women (67.12±4.74 years) practicing Pilates, divided into: non-fallers (n = 74) and fallers (n = 18). Sociodemographic data, comorbidities, medications, and Mini Mental State Examination (MMSE), Falls Efficacy Scale (FES), Confidence in Balance Scale (ABC) were applied. The examination of static balance was performed by the Clinical Test of Sensory Interaction and Balance (CTSIB). The risk of falling was analyzed using an adjusted multiple logistic regression model, while the effect of drugs on falls was estimated by binary regression, results were presented using the odds ratio (OR). The CTSIB test revealed Condition 4 (OR = 3.038; 95% CI = 1.321-15.674) and Condition 5 (OR = 5.542; 95% CI = 1.678-18.303) as predictors of falls. Drugs showing an effect on fall were β2 agonist associated with glucocorticoid (OR = 0.245; 95% CI = 1,233-2,400), thiazide diuretic (OR = 0.344; 95% CI = 1.122-2.234), statin (OR = 0.245; 95 % CI = 1,237-2,338), angiotensin II receptor antagonist (OR = 0,245; 95% CI = 1,236-2,339), beta blocker (OR = 0,245; 95% CI = 1,238-2,402) and anti-vertigo (OR = 0,245; 95 % CI = 1.230-2.399). Regardless of the history of falls, the risk of falling was present in older adult regular Pilates practitioners. Six different drugs for continuous use showed an effect on falls.
... Its hypotensive action comes from the reduction of the activity of the renin-angiotensin-aldosterone system caused by the β1 receptor blockade in the juxtapoclarular renal cells. Nebivolol can also cause orthostatic hypotension in response to changes induced by intravascular volume severity due to negative inotropic and chronotropic effects of β1 blockers 36 . All of this reduces the capacity of the heart to increase heart rate and cardiac output, increasing the risk of falls 33 . ...
The combination of types of medications can compromise the regulation of body balance in older adults. This study evaluated the effect of continuous use drugs on the sensory regulation of static balance in elderly women who regularly practice the Pilates method with and without a history of falls and estimate the risk of falls in this population. Cross-sectional study, carried out with 94 women (67.12±4.74 years) practicing Pilates, divided into: non-fallers (n = 74) and fallers (n = 18). Sociodemographic data, comorbidities, medications, and Mini Mental State Examination (MMSE), Falls Efficacy Scale (FES), Confidence in Balance Scale (ABC) were applied. The examination of static balance was performed by the Clinical Test of Sensory Interaction and Balance (CTSIB). The risk of falling was analyzed using an adjusted multiple logistic regression model, while the effect of drugs on falls was estimated by binary regression, results were presented using the odds ratio (OR). The CTSIB test revealed Condition 4 (OR = 3.038; 95% CI = 1.321–15.674) and Condition 5 (OR = 5.542; 95% CI = 1.678–18.303) as predictors of falls. Drugs showing an effect on fall were β2 agonist associated with glucocorticoid (OR = 0.245; 95% CI = 1,233–2,400), thiazide diuretic (OR = 0.344; 95% CI = 1.122–2.234), statin (OR = 0.245; 95 % CI = 1,237–2,338), angiotensin II receptor antagonist (OR = 0,245; 95% CI = 1,236–2,339), beta blocker (OR = 0,245; 95% CI = 1,238–2,402) and anti-vertigo (OR = 0,245; 95 % CI = 1.230–2.399). Regardless of the history of falls, the risk of falling was present in older adult regular Pilates practitioners. Six different drugs for continuous use showed an effect on falls.Keyword: Accidental Falls. Aging. Women´s Health. Accident Consequences.ResumoA combinação de tipos de medicamentos pode comprometer a regulação do equilíbrio corporal de idosos. Este estudo avaliou o efeito de fármacos de uso contínuo sobre a regulação sensorial do equilíbrio estático de mulheres idosas praticantes regulares do método Pilates com e sem histórico de queda e estimar o risco de queda dessa população. Estudo transversal, realizado com 94 mulheres (67,12±4,74 anos) praticantes de Pilates, divididas em: não-caidoras (n=74) e caidoras (n=18). Foram coletados dados sociodemográfico, comorbidades, medicamentos, e aplicado Mini Exame do Estado Mental (MEEM), Falls Efficacy Scale (FES), Escala de Confiança no Equilíbrio (ABC). O exame do equilíbrio estático foi realizado pelo Clinical Test of Sensory Interaction and Balance (CTSIB). O risco de queda foi analisado pelo modelo de regressão logística múltipla ajustado, enquanto, que o efeito dos fármacos sobre queda foi estimado pela regressão binária, resultados foram apresentados pelo odds ratio (OR). O teste CTSIB revelou a Condição 4 (OR= 3,038; 95% IC= 1,321–15,674) e Condição 5 (OR= 5,542; 95% IC= 1,678–18,303) como previsora de quedas. As drogas que mostram efeito sobre queda foram agonista β2 associada com glicocorticóide (OR=0,245; 95% IC= 1,233–2,400), diurético tiazídico (OR=0,344; 95% IC=1,122–2,234), estatina (OR=0,245; 95% IC=1,237–2,338), antagonista do receptor de angiotensina II (OR=0,245; 95% IC=1,236–2,339), betabloqueador (OR=0,245; 95% IC=1,238–2,402) e antivertiginoso (OR=0,245; 95% IC=1,230–2,399). Independente do histórico de quedas, o risco de cair esteve presente em idosas praticantes regulares do Pilates. Seis diferentes medicamentos de uso contínuo mostraram efeito sobre queda. Palavras-chave: Acidentes por Quedas. Envelhecimento. Saúde da Mulher. Consequências de Acidentes.
